Title:
COMPOSITION FOR PREPARING MULTI-CROSSLINKED TEMPERATURE-SENSITIVE HYDROGEL, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/282658
Kind Code:
A1
Abstract:
The present application relates to a composition for preparing a temperature-sensitive hydrogel and to a use thereof, and provides a temperature-sensitive hydrogel composition and a method for preparing a temperature-sensitive hydrogel composition by using same composition, the temperature-sensitive hydrogel composition comprising: a first agent of a liquid formulation including an aqueous solution containing chitosan and phosphate ion; and an aqueous solution containing 0.05-3.5% by weight of chitosan and 0.1-40% by weight of phosphate ion with respect to the total weight of the first agent composition.
Inventors:
CHA MI SUN (KR)
KIM SU HEE (KR)
LEE SOO HEE (KR)
KIM SU HEE (KR)
LEE SOO HEE (KR)
Application Number:
PCT/KR2022/009842
Publication Date:
January 12, 2023
Filing Date:
July 07, 2022
Export Citation:
Assignee:
MEDIFAB CO LTD (KR)
International Classes:
A61L27/52; A61F2/00; A61L15/28; A61L15/60; A61L27/20; A61L31/04; A61L31/14; C08K3/32; C08K5/053; C08L5/08
Foreign References:
| KR102100506B1 | 2020-04-13 | |||
| KR20130021385A | 2013-03-05 | |||
| KR20180117417A | 2018-10-29 | |||
| KR102415342B1 | 2022-07-04 |
Other References:
KIM EUN JI, CHOI JI SUK, KIM JUN SUNG, CHOI YOUNG CHAN, CHO YONG WOO: "Injectable and Thermosensitive Soluble Extracellular Matrix and Methylcellulose Hydrogels for Stem Cell Delivery in Skin Wounds", BIOMACROMOLECULES, AMERICAN CHEMICAL SOCIETY, US, vol. 17, no. 1, 11 January 2016 (2016-01-11), US , pages 4 - 11, XP093022652, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.5b01566
MEKHAIL MINA, MARYAM TABRIZIAN: "Injectable Chitosan-Based Scaffolds in Regenerative Medicine and their Clinical Translatability", ADVANCED HEALTHCARE MATERIALS, vol. 3, no. 10, 10 March 2014 (2014-03-10), pages 1529 - 1545, XP093022654, DOI: 10.1002/adhm.201300586
MEKHAIL MINA, MARYAM TABRIZIAN: "Injectable Chitosan-Based Scaffolds in Regenerative Medicine and their Clinical Translatability", ADVANCED HEALTHCARE MATERIALS, vol. 3, no. 10, 10 March 2014 (2014-03-10), pages 1529 - 1545, XP093022654, DOI: 10.1002/adhm.201300586
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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