COMPOSITION FOR PREPARING RETINOID, AND METHOD FOR PREPARING RETINOID USING SAME

Title:

COMPOSITION FOR PREPARING RETINOID, AND METHOD FOR PREPARING RETINOID USING SAME

Document Type and Number:

WIPO Patent Application WO/2023/085688

Kind Code:

A1

Abstract:

The present invention relates to a composition for preparing retinoid, and more specifically, the composition comprises: NADH or NADPH; a beta-carotene oxygenase; and a flavodoxin or ferredoxin, a reductase of a flavodoxin or ferredoxin, a microorganism expressing the same, or a cultured product or a ground product of the microorganism, and thus can expand the supply metabolism of reducing electrons to enhance retinoid productivity through an increase in the activity of the cytochrome P450 system and provide a foundation for the low-cost production of raw materials, and thereby enhance the economic feasibility and efficiency of retinoid production.

Inventors:

KIM SEON WON (KR)
PARK JI BIN (KR)
JEONG SEONG HEE (KR)
KWON MOON HYUK (KR)

Application Number:

PCT/KR2022/017114

Publication Date:

May 19, 2023

Filing Date:

November 03, 2022

Export Citation:

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Assignee:

NAT UNIV GYEONGSANG IACF (KR)

International Classes:

C12P23/00; C07K14/245; C12N9/02; C12N9/10; C12N9/12; C12N15/70

Foreign References:

KR20160019480A	2016-02-19
KR20190113851A	2019-10-08
KR20130014445A	2013-02-07
KR20210041657A	2021-04-16

Other References:

ANONYMOUS: "Building Platform for Terpenoids Metabolic Engineering Through Systems/Synthetic Biological Approaches", FINAL REPORT OF COMPLETED PROJECT (PROJECT NO.: PJ008184), NATIONAL INSTITUTE OF AGRICULTURAL SCIENCES, KOREA, 1 February 2013 (2013-02-01), Korea, pages 1 - 76, XP009546975, DOI: 10.23000/TRKO201300014289