Title:
COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING ARTERIOSCLEROSIS, CONTAINING CANNABIS SATIVA L. STEM EXTRACT AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2021/118142
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing, alleviating, or treating arteriosclerosis, containing Cannabis sativa L. stem extract as an active ingredient. It has been identified that a Cannabis sativa L. stem extract shows almost no cytotoxicity and reduces the amount of intracellular lipid and the expression of cholesterol biosynthesis pathway-related genes and increases the expression of genes for discharging cholesterol. Therefore, it is expected that a Cannabis sativa L. stem extract, which is an active ingredient of the present invention, is effectively usable as a composition for preventing, alleviating, or treating arteriosclerosis.
Inventors:
CHA MIN-HO (KR)
YIM NAM HUI (KR)
GO YOUNGHOON (KR)
OH YOU CHANG (KR)
YIM NAM HUI (KR)
GO YOUNGHOON (KR)
OH YOU CHANG (KR)
Application Number:
PCT/KR2020/017285
Publication Date:
June 17, 2021
Filing Date:
November 30, 2020
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A23L33/105; A23L5/20; A23L19/00; A61K36/185; A61P9/10
Domestic Patent References:
| WO2018228616A1 | 2018-12-20 |
Foreign References:
| KR20190091316A | 2019-08-05 | |||
| KR20130113581A | 2013-10-16 | |||
| JP2011509989A | 2011-03-31 |
Other References:
SINGLA SANDEEP, SACHDEVA RAJESH, MEHTA JAWAHAR L.: "Cannabinoids and Atherosclerotic Coronary Heart Disease", CLINICAL CARDIOLOGY (HOBOKEN), JOHN WILEY & SONS, INC., US, vol. 35, no. 6, 1 June 2012 (2012-06-01), US, pages 329 - 335, XP055820954, ISSN: 0160-9289, DOI: 10.1002/clc.21962
ANONYMOUS: "Checking the effectiveness of arteriosclerosis treatment of cannabis extracts", AKOMNEWS, 13 May 2020 (2020-05-13), XP055820956, Retrieved from the Internet
ANONYMOUS: "Checking the effectiveness of arteriosclerosis treatment of cannabis extracts", AKOMNEWS, 13 May 2020 (2020-05-13), XP055820956, Retrieved from the Internet
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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