Title:
COMPOSITION FOR PREVENTING OR TREATING CANCER BY USING MATURATION INDUCTION OF IMMATURE DENDRITIC CELLS
Document Type and Number:
WIPO Patent Application WO/2022/197124
Kind Code:
A1
Abstract:
The present invention relates to a composition for cancer prevention or treatment by using maturation induction of immature dendritic cells and, particularly, to a composition for cancer prevention or treatment by using Leuconostoc mesenteroides LB-LM1 strain (accession number: KCCM12701P) to mature immature dendritic cells, whereby an immune response of T lymphocytes to cancer cells can be induced. A composition comprising, as an active ingredient, dendritic cells matured using a microorganism, according to the present invention, exhibits excellent anticancer activity in an animal model, and as such may be effectively used as a composition for treatment, prevention, or alleviation of cancer in humans or animals.
More Like This:
Inventors:
CHIN HWA SUP (KR)
Application Number:
PCT/KR2022/003764
Publication Date:
September 22, 2022
Filing Date:
March 17, 2022
Export Citation:
Assignee:
LISCURE BIOSCIENCES CO LTD (KR)
International Classes:
A61K35/15; A23K10/10; A23L33/10; A61P35/00; C12N5/0784
Foreign References:
| US20070031441A1 | 2007-02-08 | |||
| KR101941139B1 | 2019-01-22 | |||
| KR101909999B1 | 2018-10-19 | |||
| KR101041440B1 | 2011-06-15 |
Other References:
MATSUZAKI CHIAKI, TAKAGAKI CHIKAHIRO, HIGASHIMURA YASUKI, NAKASHIMA YUKARI, HOSOMI KOJI, KUNISAWA JUN, YAMAMOTO KENJI, HISA KEIKO: "Immunostimulatory effect on dendritic cells of the adjuvant-active exopolysaccharide from Leuconostoc mesenteroides strain NTM048", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, JP, vol. 82, no. 9, 2 September 2018 (2018-09-02), JP , pages 1647 - 1651, XP055967004, ISSN: 0916-8451, DOI: 10.1080/09168451.2018.1482195
Attorney, Agent or Firm:
HAN, Kwang Hyun (KR)
Download PDF: