Title:
COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING ANTI-CD300C MONOCLONAL ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2021/101244
Kind Code:
A1
Abstract:
The present invention relates to: anti-CD300C monoclonal antibodies; a composition for preventing or treating cancer, comprising same; an anticancer immunotherapy composition comprising same; and the like. Anti-CD300C monoclonal antibodies according to the present invention bind to a CD300c antigen with high specificity and also promote anticancer immune effects, and thus are expected to be effectively used against various cancer growth, development, metastasis and the like.
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Inventors:
JEON JAEWON (KR)
LEE SUIN (KR)
JUNG JOONGOO (KR)
KIM WOOCHANG (KR)
YOON MINJI (KR)
YEOM JUNHO (KR)
SEO JEONGEUN (KR)
HAN JAEWOONG (KR)
LEE SUIN (KR)
JUNG JOONGOO (KR)
KIM WOOCHANG (KR)
YOON MINJI (KR)
YEOM JUNHO (KR)
SEO JEONGEUN (KR)
HAN JAEWOONG (KR)
Application Number:
PCT/KR2020/016264
Publication Date:
May 27, 2021
Filing Date:
November 18, 2020
Export Citation:
Assignee:
CENTRICS BIO (KR)
International Classes:
A61K39/395; A61K31/713; A61K45/06; A61P35/00; C07K16/28
Domestic Patent References:
| WO2018094460A1 | 2018-05-31 |
Foreign References:
| US20160194631A1 | 2016-07-07 | |||
| KR20190136949A | 2019-12-10 | |||
| KR20180099557A | 2018-09-05 |
Other References:
CHENG CUI, MIN SU, YUJUN LIN, LAIJUN LAI: "A CD300c-Fc fusion protein inhibits T cell immunity", FRONTIERS IN IMMUNOLOGY, vol. 9, 15 November 2018 (2018-11-15), pages 1 - 14, XP055660033, DOI: 10.3389/fimmu.2018.02657
VENKATESWARA R. SIMHADRI, MARIANO JOHN L., GIL-KRZEWSKA ALEKSANDRA, ZHOU QING, BORREGO FRANCISCO: "CD300c is an Activating Receptor Expressed on Human Monocytes", JOURNAL OF INNATE IMMUNITY, S. KARGER AG, CH, vol. 5, no. 4, 6 April 2013 (2013-04-06), CH, pages 389 - 400, XP055660026, ISSN: 1662-811X, DOI: 10.1159/000350523
MILENA DIMITROVA, ZENARRUZABEITIA OLATZ, BORREGO FRANCISCO, SIMHADRI VENKATESWARA R.: "CD300c is uniquely expressed on CD56bright Natural Killer Cells and differs from CD300a upon ligand recognition", SCIENTIFIC REPORTS, vol. 6, no. 1, 4 April 2016 (2016-04-04), pages 1 - 12, XP055660025, DOI: 10.1038/srep23942
See also references of EP 4062934A4
VENKATESWARA R. SIMHADRI, MARIANO JOHN L., GIL-KRZEWSKA ALEKSANDRA, ZHOU QING, BORREGO FRANCISCO: "CD300c is an Activating Receptor Expressed on Human Monocytes", JOURNAL OF INNATE IMMUNITY, S. KARGER AG, CH, vol. 5, no. 4, 6 April 2013 (2013-04-06), CH, pages 389 - 400, XP055660026, ISSN: 1662-811X, DOI: 10.1159/000350523
MILENA DIMITROVA, ZENARRUZABEITIA OLATZ, BORREGO FRANCISCO, SIMHADRI VENKATESWARA R.: "CD300c is uniquely expressed on CD56bright Natural Killer Cells and differs from CD300a upon ligand recognition", SCIENTIFIC REPORTS, vol. 6, no. 1, 4 April 2016 (2016-04-04), pages 1 - 12, XP055660025, DOI: 10.1038/srep23942
See also references of EP 4062934A4
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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