Title:
COMPOSITION FOR PREVENTING OR TREATING CLIMACTERIC SYMPTOMS, COMPRISING LACTOBACILLUS FERMENTUM
Document Type and Number:
WIPO Patent Application WO/2022/045513
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or treating climacteric symptoms, comprising Lactobacillus fermentum. Particularly, the present invention relates to a food composition for preventing or alleviating climacteric or menopausal symptoms and a pharmaceutical composition for preventing or treating climacteric or menopausal symptoms, the compositions containing, as an active ingredient, a Lactobacillus fermentum strain, a culture product thereof or a fermentation product thereof. A Lactobacillus fermentum of the present invention or a fermentation product thereof can improve and promote intestinal health through intestinal microflora changes, barrier strengthening, and intestinal inflammation inhibition during menopause or menopause accompanied by inflammation, and, furthermore, can increase bone density that was reduced during menopause or menopause accompanied by inflammation, and thus is usable in the preparation of a health functional food and a medical product enabling effective prevention, alleviation or treatment of menopausal or climacteric symptoms through regulation of intestine-bone metabolism and regulation of the immune system.
Inventors:
KIM SAE HUN (KR)
EOR JU YOUNG (KR)
EOR JU YOUNG (KR)
Application Number:
PCT/KR2021/003735
Publication Date:
March 03, 2022
Filing Date:
March 25, 2021
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
A23L33/135; A61K35/747; A61P15/12
Domestic Patent References:
| WO2020080736A1 | 2020-04-23 |
Foreign References:
| KR20180103772A | 2018-09-19 | |||
| KR20200087900A | 2020-07-22 | |||
| US20120189599A1 | 2012-07-26 |
Other References:
AYYANNA REPALLY, ANKAIAH DASARI, ARUL VENKATESAN: "Anti-inflammatory and Antioxidant Properties of Probiotic Bacterium Lactobacillus mucosae AN1 and Lactobacillus fermentum SNR1 in Wistar Albino Rats", FRONTIERS IN MICROBIOLOGY, vol. 9, 14 December 2018 (2018-12-14), XP055903068, DOI: 10.3389/fmicb.2018.03063
JEONG SEONG-YEOP, KANG SUNA, HUA CAO SHI, TING ZHANG, PARK SUNMIN: "Synbiotic effects of β-glucans from cauliflower mushroom and Lactobacillus fermentum on metabolic changes and gut microbiome in estrogen-deficient rats", GENES & NUTRITION ; STUDYING THE RELATIONSHIP BETWEEN GENETICS AND NUTRITION IN THE IMPROVEMENT OF HUMAN HEALTH, BERLIN ; HEIDELBERG : SPRINGER, DE, vol. 12, no. 1, 1 December 2017 (2017-12-01), DE , XP055903069, ISSN: 1555-8932, DOI: 10.1186/s12263-017-0585-z
JEONG SEONG-YEOP, KANG SUNA, HUA CAO SHI, TING ZHANG, PARK SUNMIN: "Synbiotic effects of β-glucans from cauliflower mushroom and Lactobacillus fermentum on metabolic changes and gut microbiome in estrogen-deficient rats", GENES & NUTRITION ; STUDYING THE RELATIONSHIP BETWEEN GENETICS AND NUTRITION IN THE IMPROVEMENT OF HUMAN HEALTH, BERLIN ; HEIDELBERG : SPRINGER, DE, vol. 12, no. 1, 1 December 2017 (2017-12-01), DE , XP055903069, ISSN: 1555-8932, DOI: 10.1186/s12263-017-0585-z
Attorney, Agent or Firm:
NAM & NAM (KR)
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