Title:
COMPOSITION FOR PRODUCTION OF GINSENOSIDE COMPOUND K COMPRISING HIGH TEMPERATURE α-L-ARABINOFURANOSIDASE, AND METHOD FOR PREPARING GINSENOSIDE COMPOUND K
Document Type and Number:
WIPO Patent Application WO/2018/062904
Kind Code:
A1
Abstract:
Disclosed are a composition for production of ginsenoside compound K using a high temperature-β-glycosidase and a high temperature-α-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow high temperature-β-glycosidase and high temperature-α-L-arabinofuranosidase to exhibit stable activity even at high temperatures, thereby increasing a reaction rate. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow a large quantity of ginsenoside compound k to be produced in a short time, thereby exhibiting an effect of producing a high yield, and thus can be utilized industrially.
Inventors:
PARK JUNSEONG (KR)
HWANG KYEONGHWAN (KR)
OH DEOK-KUN (KR)
SHIN KYUNG-CHUL (KR)
HWANG KYEONGHWAN (KR)
OH DEOK-KUN (KR)
SHIN KYUNG-CHUL (KR)
Application Number:
PCT/KR2017/010849
Publication Date:
April 05, 2018
Filing Date:
September 28, 2017
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
UNIV KONKUK IND COOP CORP (KR)
UNIV KONKUK IND COOP CORP (KR)
International Classes:
C12P33/16; C07J17/00; C12N9/24; C12N9/42; C12P19/44
Foreign References:
| KR20160031245A | 2016-03-22 | |||
| KR20070035499A | 2007-03-30 | |||
| KR20110125422A | 2011-11-21 |
Other References:
DATABASE Protein [O] 28 January 2014 (2014-01-28), XP055500924, Database accession no. ABQ46651.1
SHIN, KYUNG-CHUL ET AL.: "Complete Conversion of Major Protopanaxadiol Ginsenosides to Compound K by the Combined Use of a-L-arabinoiuranosidase and beta-galactosidase from Caldicellulosiruptor Saccharolyticus and beta-glucosidase from Sulfolobus Acidocaldarius", JOURNAL OF BIOTECHNOLOGY, vol. 167, 14 June 2013 (2013-06-14), pages 33 - 40, XP055500926
SHIN, KYUNG-CHUL ET AL.: "Complete Conversion of Major Protopanaxadiol Ginsenosides to Compound K by the Combined Use of a-L-arabinoiuranosidase and beta-galactosidase from Caldicellulosiruptor Saccharolyticus and beta-glucosidase from Sulfolobus Acidocaldarius", JOURNAL OF BIOTECHNOLOGY, vol. 167, 14 June 2013 (2013-06-14), pages 33 - 40, XP055500926
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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