Title:
COMPOSITION FOR REDUCING BLOOD PRESSURE AND/OR FOR REDUCING NEUTRAL FATS
Document Type and Number:
WIPO Patent Application WO/2019/160024
Kind Code:
A1
Abstract:
Provided is a composition for reducing blood pressure and/or reducing neutral fats that has few side effects and is very safe. The composition for reducing blood pressure and/or for reducing neutral fats comprises a casein hydrolysate and digestion-resistant dextrin. Ideally, the casein hydrolysate contains a peptide comprising Met-Lys-Pro. Ideally, the casein hydrolysate contains a peptide comprising Met-Lys-Pro and the composition comprises 5000-100000 parts by mass of digestion-resistant dextrin with respect to 1 part by mass of said peptide.
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Inventors:
TADA ASUKA (JP)
TANAKA MIYUKI (JP)
OCHI DAISUKE (JP)
HORIGOME MIYAKO (JP)
YANAGISAWA EIKO (JP)
TANAKA MIYUKI (JP)
OCHI DAISUKE (JP)
HORIGOME MIYAKO (JP)
YANAGISAWA EIKO (JP)
Application Number:
PCT/JP2019/005301
Publication Date:
August 22, 2019
Filing Date:
February 14, 2019
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A23L2/00; A61K38/17; A23L33/18; A23L33/21; A61K31/718; A61P3/06; A61P9/12; C07K5/062
Domestic Patent References:
| WO2003044044A1 | 2003-05-30 | |||
| WO2013125622A1 | 2013-08-29 | |||
| WO2010113785A1 | 2010-10-07 |
Foreign References:
| JP2017031105A | 2017-02-09 | |||
| JP2000135055A | 2000-05-16 | |||
| JP4540231B2 | 2010-09-08 | |||
| JP2009167172A | 2009-07-30 | |||
| JPH05176713A | 1993-07-20 | |||
| JP2015036376A | 2015-02-23 | |||
| JP2016069343A | 2016-05-09 | |||
| JP2001252064A | 2001-09-18 | |||
| JP2016069343A | 2016-05-09 | |||
| JPH0491765A | 1992-03-25 | |||
| JP2017031105A | 2017-02-09 | |||
| JP2017184682A | 2017-10-12 | |||
| JPH03169888A | 1991-07-23 | |||
| JPH06228179A | 1994-08-16 |
Other References:
KIYOSHISA KANEKO , SHINSUKE NAKAGAWA , SUMIO KONDO , KUMIE ITO , YAESU SAKUADORI: "Suppression of increase in postprandial neutral fat in blood by ingestion of indigestible dextrin-containing tea beverage - A randomized, placebo-controlled, double-blind, cross-over study", JAPANESE PHARMACOLOGY AND THERAPEUTICS , vol. 44, no. 2, 30 November 2015 (2015-11-30), pages 263 - 270, XP009523083, ISSN: 0386-3603
KISHIMOTO, YUKA: "Development of foods with function claims, using Matsutani Chemical's functional ingredients (indigestible dextrin, rare sugar syrup", A TECHNICAL JOURNAL ON FOOD CHEMISTRY & CHEMICALS, vol. 373, 2016, pages 77 - 80, XP009523085, ISSN: 0911-2286
DAISUKE OCHI, AKIO YAMADA, KOJI YAMAUCHI, FUMIAKI ABE, YASUO THO: "Blood Pressure-lowering Effects of Casein-derived Peptide Met-Lys-Pro in Subjects with High-normal Blood Pressure and Grade 1 Hypertension — A Randomized, Double-blind, Placebo-controlled, Parallel-group, Trial —", JAPANESE PHARMACOLOGY & THERAPEUTICS, vol. 45, no. 10, 2017, pages 1637 - 1648, XP009523084, ISSN: 0386-3603
ANONYMOUS: "Indigestible dextrin", CONSIGNMENT OF THE MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES FOOD AND MARKETING BUREAU, TECHNOLOGY SERIES NO. 9 FOR THE EFFECTIVE UTILIZATION OF DIETARY FUNCTIONAL MATERIALS, vol. 9, 1991, pages 1 - 25, XP009523171
"Basic High Polymer Science", 1978, TOKYO KAGAKU DOJIN CO. LTD., pages: 116 - 119
"Analytical Methods for Nutrients on the Standards for Nutrition Labeling", EISHIN, no. 13, 26 April 1999 (1999-04-26)
KAZUHIRO OKUMAISAO MATSUDA: "Indigestible Fractions of Starch Hydrolysates and Their Determination Method", J. APPL. GLYCOSCI., vol. 49, no. 4, 2002, pages 479 - 485
KAZUHIRO OHKUMAISAO MATSUDAYASUO KATTAYOSHIO HANNO: "Pyrolysis of Starch and Its Digestibility by Enzymes", CHARACTERIZATION OF INDIGESTIBLE DEXTRIN
DENPUN KAGAKU, vol. 37, no. 2, 1990, pages 107 - 114
KAZUHIRO OHKUMAISAO MATSUDA: "Production of Indigestible Dextrin from Pyrodextrin", J. APPL. GLYCOSCI., vol. 50, no. 3, 2003, pages 389 - 394, XP008044753
"New Food Processing Lecture: Milk and Its Processing (saishin shokuhinkakokoza: nyu to sono kako)", 1987, KENPAKUSHA CO., LTD., pages: 282
See also references of EP 3753569A4
KISHIMOTO, YUKA: "Development of foods with function claims, using Matsutani Chemical's functional ingredients (indigestible dextrin, rare sugar syrup", A TECHNICAL JOURNAL ON FOOD CHEMISTRY & CHEMICALS, vol. 373, 2016, pages 77 - 80, XP009523085, ISSN: 0911-2286
DAISUKE OCHI, AKIO YAMADA, KOJI YAMAUCHI, FUMIAKI ABE, YASUO THO: "Blood Pressure-lowering Effects of Casein-derived Peptide Met-Lys-Pro in Subjects with High-normal Blood Pressure and Grade 1 Hypertension — A Randomized, Double-blind, Placebo-controlled, Parallel-group, Trial —", JAPANESE PHARMACOLOGY & THERAPEUTICS, vol. 45, no. 10, 2017, pages 1637 - 1648, XP009523084, ISSN: 0386-3603
ANONYMOUS: "Indigestible dextrin", CONSIGNMENT OF THE MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES FOOD AND MARKETING BUREAU, TECHNOLOGY SERIES NO. 9 FOR THE EFFECTIVE UTILIZATION OF DIETARY FUNCTIONAL MATERIALS, vol. 9, 1991, pages 1 - 25, XP009523171
"Basic High Polymer Science", 1978, TOKYO KAGAKU DOJIN CO. LTD., pages: 116 - 119
"Analytical Methods for Nutrients on the Standards for Nutrition Labeling", EISHIN, no. 13, 26 April 1999 (1999-04-26)
KAZUHIRO OKUMAISAO MATSUDA: "Indigestible Fractions of Starch Hydrolysates and Their Determination Method", J. APPL. GLYCOSCI., vol. 49, no. 4, 2002, pages 479 - 485
KAZUHIRO OHKUMAISAO MATSUDAYASUO KATTAYOSHIO HANNO: "Pyrolysis of Starch and Its Digestibility by Enzymes", CHARACTERIZATION OF INDIGESTIBLE DEXTRIN
DENPUN KAGAKU, vol. 37, no. 2, 1990, pages 107 - 114
KAZUHIRO OHKUMAISAO MATSUDA: "Production of Indigestible Dextrin from Pyrodextrin", J. APPL. GLYCOSCI., vol. 50, no. 3, 2003, pages 389 - 394, XP008044753
"New Food Processing Lecture: Milk and Its Processing (saishin shokuhinkakokoza: nyu to sono kako)", 1987, KENPAKUSHA CO., LTD., pages: 282
See also references of EP 3753569A4
Attorney, Agent or Firm:
WATANABE Kaoru (JP)
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