Title:
COMPOSITION THAT CONTAINS PLANT- OR ANIMAL-DERIVED PEPTIDE AND INHIBITS SERUM CARNOSINASE
Document Type and Number:
WIPO Patent Application WO/2017/010538
Kind Code:
A1
Abstract:
Provided are a carnosine dipeptidase 1 inhibitor composition, a use for a material that inhibits carnosine dipeptidase 1, and a method for inhibiting carnosine dipeptidase 1. The present invention demonstrates the discovery of a plant- or animal-derived peptide exhibiting an inhibitory activity against carnosine dipeptidase 1, and thus, provides a novel and effective means that contributes to the prevention or amelioration of a cognitive function decline or the like.
Inventors:
FUKIZAWA SHINYA (JP)
WATANABE HIROSHI (JP)
ABE KEIICHI (JP)
TAKANO JIRO (JP)
WATANABE HIROSHI (JP)
ABE KEIICHI (JP)
TAKANO JIRO (JP)
Application Number:
PCT/JP2016/070798
Publication Date:
January 19, 2017
Filing Date:
July 14, 2016
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
A61K38/00; A61K36/48; A61K36/82; A61K38/17; A61P3/10; A61P9/00; A61P25/00; A61P25/28; A61P29/00; A61P37/02; A61P39/06; A61P43/00
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Other References:
MOKUTEKI, KYOTO-FURITSU CHAGYO KENKYUSHO SHIKEN KENKYU SEISEKISHO HEISEI 15 NENDO GAIYOSHU, vol. 223-07, 2004, pages 1 - 2
JIN, WEIGANG ET AL.: "Development and utilization of tea residue as a resource - study on the functional properties of tea peptides", JOURNAL OF CHINESE INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY, vol. 11, no. 5, 2011, pages 52 - 58, ISSN: 1009-7848
NAEMI KAJIWARA ET AL.: "Studies on nutritional and physiological characteristics of peptides derived from collagen", REPORTS OF THE RESEARCH COMMITTEE OF ESSENTIAL AMINO ACIDS ( JAPAN, 1994, pages 43 - 46, ISSN: 0387-4141
ZOLOTAREV, Y A ET AL.: "Short peptide fragments with antiulcer activity from a collagen hydrolysate", RUSSIAN JOURNAL OF BIOORGANIC CHAMISTRY, vol. 32, no. 2, 2006, pages 174 - 178, XP019300017, ISSN: 1068-1620
ZHAO, H H ET AL.: "Collagen peptides protects human hepatocytes against hydrogen peroxide (H202)-induced oxidative stress damage: Involvement of the Nrf2 transcription factor", PROGRESS IN MODERN BIOMEDICINE, vol. 14, no. 23, 2014, pages 4434 - 4439, ISSN: 1673-6273
KEISUKE ITO ET AL.: "Hito Dipeptidyl Peptidase IV Sogai Sayo o Yusuru ''Ryokucha Peptide'' no Kaihatsu", PROCEEDINGS OF JAPANESE SOCIETY OF FOOD SCIENCE AND TECHNOLOGY, vol. 62, 27 August 2015 (2015-08-27), pages 124, [retrieved on 20160420]
JIN, WEIGANG ET AL.: "Development and utilization of tea residue as a resource - study on the functional properties of tea peptides", JOURNAL OF CHINESE INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY, vol. 11, no. 5, 2011, pages 52 - 58, ISSN: 1009-7848
NAEMI KAJIWARA ET AL.: "Studies on nutritional and physiological characteristics of peptides derived from collagen", REPORTS OF THE RESEARCH COMMITTEE OF ESSENTIAL AMINO ACIDS ( JAPAN, 1994, pages 43 - 46, ISSN: 0387-4141
ZOLOTAREV, Y A ET AL.: "Short peptide fragments with antiulcer activity from a collagen hydrolysate", RUSSIAN JOURNAL OF BIOORGANIC CHAMISTRY, vol. 32, no. 2, 2006, pages 174 - 178, XP019300017, ISSN: 1068-1620
ZHAO, H H ET AL.: "Collagen peptides protects human hepatocytes against hydrogen peroxide (H202)-induced oxidative stress damage: Involvement of the Nrf2 transcription factor", PROGRESS IN MODERN BIOMEDICINE, vol. 14, no. 23, 2014, pages 4434 - 4439, ISSN: 1673-6273
KEISUKE ITO ET AL.: "Hito Dipeptidyl Peptidase IV Sogai Sayo o Yusuru ''Ryokucha Peptide'' no Kaihatsu", PROCEEDINGS OF JAPANESE SOCIETY OF FOOD SCIENCE AND TECHNOLOGY, vol. 62, 27 August 2015 (2015-08-27), pages 124, [retrieved on 20160420]
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
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