Title:
COMPOSITION THAT RECOGNIZES ANTIBODIES STEMMING FROM IMMUNE-MEDIATED PERIPHERAL NEUROPATHY AND USE FOR SAID COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2014/136974
Kind Code:
A1
Abstract:
Sugar-chain-immobilized fluorescent nanoparticles that allow quick and convenient detection of ganglioside-binding autoantibodies in blood serum from immune-mediated peripheral neuropathy patients are provided, as is a use for said sugar-chain-immobilized fluorescent nanoparticles. These sugar-chain-immobilized fluorescent nanoparticles contain the following: sugar-chain ligand complexes comprising sugar chains, including ganglioside-derived sugar chains, and a prescribed linker compound that has a hydrocarbon chain or the like on the main chain thereof; and fluorescent nanoparticles that have a prescribed core-shell structure. These sugar-chain-immobilized fluorescent nanoparticles are obtained by immobilizing the abovementioned sugar chains.
More Like This:
Inventors:
SUDA YASUO (JP)
WAKAO MASAHIRO (JP)
ISHIDA HIDEHARU (JP)
YUKI NOBUHIRO (SG)
WAKAO MASAHIRO (JP)
ISHIDA HIDEHARU (JP)
YUKI NOBUHIRO (SG)
Application Number:
PCT/JP2014/056073
Publication Date:
September 12, 2014
Filing Date:
March 07, 2014
Export Citation:
Assignee:
SUDX BIOTEC CORP (JP)
NAT UNIV CORP KAGOSHIMA (JP)
NAT UNIVERSITY CORP GIFU UNIVERSITY (JP)
NAT UNIV CORP KAGOSHIMA (JP)
NAT UNIVERSITY CORP GIFU UNIVERSITY (JP)
International Classes:
G01N33/553; B82Y5/00; B82Y40/00; G01N33/53; G01N33/533
Foreign References:
JP2011209282A | 2011-10-20 | |||
JP2008105978A | 2008-05-08 | |||
JP2010122011A | 2010-06-03 | |||
JPH11142404A | 1999-05-28 | |||
JP2013040970A | 2013-02-28 | |||
US20050130240A1 | 2005-06-16 | |||
US20060068506A1 | 2006-03-30 | |||
US20080039816A1 | 2008-02-14 |
Other References:
YUKI N ET AL.: "Animal model of axonal Guillain- Barre' syndrome induced by sensitization with GM1 ganglioside", ANN NEUROL, vol. 9, no. 6, pages 712 - 720
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
Patent business corporation HARAKENZO WORLD PATENT & TRADEMARK (JP)
Patent business corporation HARAKENZO WORLD PATENT & TRADEMARK (JP)
Download PDF: