BREY CHAD (US)
CLAIMS What is claimed is: 1. A composition comprising: a cannabidiol (CBD), a flavanone, or a salt thereof; and one or more of: a glucosamine, a salt thereof, a glycosaminoglycan, a salt thereof, a vitamin, a derivative thereof, a salt thereof, or methylsulfonylmethane (MSM). 2. The composition of claim 1, wherein the composition is in the form of a capsule, a tablet, a gummy, an oil, a tincture, a lotion, a cream, a balm, a candy, a chocolate, a food, a drink, a liquid, an oil, a syrup, or any combination thereof. 3. The composition of claim 1, wherein the composition further comprises: a monoterpene, a derivative thereof, a salt thereof, or any combination thereof. 4. The composition of claim 1, wherein the composition further comprises: a mineral, a salt thereof, or a chelated form thereof, an amino acid or a salt thereof, at least a portion of a plant or an extract thereof, an oil, a fatty acid, or any combination thereof. 5. The composition of claim 1, wherein the composition further comprises: a sugar, a sucralose, an aspartame, a stevia, or any combination thereof. 6. The composition of claim 1, wherein the composition comprises substantially no Δ9- tetrahydrocannabinol (THC). 7. The composition of claim 1, wherein the composition further comprises Δ8-THC. 8. The composition of claim 1, wherein the composition is a dietary supplement and is in the form of a capsule, a gummy, a candy, a chocolate, a beverage, a food, a liquid, an oil, a syrup or any combination thereof; or is medical food and is in the form of a capsule, a gummy, a candy, a chocolate, a beverage, a food, a liquid, an oil, a syrup, or any combination thereof . 9. The composition of claim 1, wherein the CBD comprises cannabidiol, cannabidiolic acid, or any combination thereof. 10. The composition of claim 1, wherein the CBD is formulated as a powder, an oil, a liquid, or any combination thereof. 11. The composition of claim 10, wherein the CBD is at least partially water soluble. 12. The composition of claim 1, comprising the flavanone or salt thereof which comprises naringenin, a salt thereof, a derivative of naringenin, a salt thereof, naringin, a salt thereof, a derivative of naringin, a salt thereof, or any combination thereof. 13. The composition of claim 12, wherein the flavanone is in the form of an extract from: a grapefruit, a sour orange, a tart cherry, a citrus fruit, a tomato or any combination thereof. 14. The composition of claim 1, comprising the salt of glucosamine which comprises glucosamine sulfate. 15. The composition of claim 1, comprising the salt of glycosaminoglycan which comprises chondroitin sulfate, dermatan sulfate, or any combination thereof. 16. The composition of claim 1, comprising the glycosaminoglycan or salt thereof which comprises hyaluronan or a salt thereof. 17. The composition of claim 1, comprising the salt of glycosaminoglycan which comprises keratan sulfate. 18. The composition of claim 1, comprising the vitamin, the derivative thereof, or the salt thereof which comprises: vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B7, vitamin B9, vitamin B12, a derivative of any of these, a salt of any of these, or any combination thereof. 19. The composition of claim 18, comprising the vitamin C or salt thereof. 20. The composition of claim 19, comprising the salt of vitamin C which comprises calcium ascorbate. 21. The composition of claim 3, comprising the monoterpene or salt thereof which comprises D-limonene or a salt thereof. 22. The composition of claim 4, comprising the mineral, the chelated form thereof, the salt thereof, or any combination thereof which comprises: a calcium, a phosphorus, a potassium, a sulfur, a sodium, a chloride, a magnesium, an iron, a zinc, a copper, a manganese, an iodine, a selenium, a molybdenum, a chromium, a fluoride, a chelated form thereof, a salt thereof, or any combination thereof. 23. The composition of claim 4, comprising the at least the portion of the plant or the extract thereof which comprises: Boswellia serrata, lemon grass, eucalyptus, bromelain, capsaicin, cat’s claw, curcumin, evening primrose, ginger, gingko, green tea, flaxseed, pine bar, rose hips, St. John’s wort, Devil's claw, hemp, stinging nettle, thunder god vine, valerian root, any portion thereof, any extract thereof, a tincture thereof, or any combination thereof. 24. The composition of claim 4, comprising the oil which comprises: fish oil, avocado oil, soybean oil, black currant oil, lemon grass oil, eucalyptus oil, frankincense oil, medium-chain triglyceride (MCT) oil, hemp oil, borage oil, or any combination thereof. 25. The composition of claim 4, comprising the fatty acid, which comprises a short chain fatty acid, a medium chain fatty acid, a long chain fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. 26. The composition of claim 4, comprising the fatty acid, which comprises a saturated fatty acid, an unsaturated fatty acid, a monounsaturated fatty acid, a polyunsaturated fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. 27. The composition of claim 26, comprising the saturated fatty acid, the unsaturated fatty acid, the monounsaturated fatty acid, the polyunsaturated fatty acid, or any combination thereof which comprises arachidonic acid, linoleic acid, palmitic acid, oleic acid, adrenic acid, docosapentaenoic acid, mead acid, an ester of any of these, a salt of any of these, or any combination thereof. 28. The composition of claim 4, comprising the fatty acid, which comprises an omega-3 fatty acid, an omega-6 fatty acid, an omega-9 fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. 29. The composition of claim 28, comprising the omega-3 fatty acid, which comprises eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), alpha-linolenic acid (ALA), an ester of any of these, a salt of any of these, or any combination thereof. 30. The composition of claim 2, wherein the composition is in the form of the capsule, and wherein the capsule is a hydroxymethylcellulose capsule. 31. The composition of claim 2, wherein the composition is in the form of the candy, and wherein the candy is in the form of: a caramel, a fruit candy drop, or any combination thereof. 32. The composition of claim 2, wherein the composition is in the form of the chocolate, and wherein the chocolate is in the form of: a blueberry chocolate, a cranberry chocolate, a fruit flavored chocolate, a citrus flavored chocolate, a fruit covered chocolate, a chocolate bar, a chocolate caramel, a coffee bean chocolate or any combination thereof. 33. The composition of claim 2, wherein the composition is in the form of the balm, and wherein the balm further comprises shea butter, cocoa butter, bees wax, or any combination thereof. 34. The composition of claim 2, wherein the composition is in the form of the cream, and wherein the cream further comprises hemp cream. 35. The composition of claim 2, wherein the composition is in the form of the gummy, and wherein the gummy further comprises carrageenan. 36. A method comprising administering the composition of any one of claims 1-35 to a subject, wherein the composition is in unit dose form. 37. The method of claim 36, wherein the administering is by oral ingestion, topical application, or inhalation. 38. The method of claim 37, comprising the oral ingestion which comprises oral ingestion of a food, a liquid, a gel, a capsule, or any combination thereof. 39. The method of claim 37, comprising the topical application which comprises topical application of a lotion, a tincture, a balm, a cream, an oil, a gel, a butter, a liquid, a spray, an ointment, a paste, a jelly, or any combination thereof. 40. The method of claim 37, comprising the inhalation which comprises inhalation by a diffuser. 41. The method of claim 36, wherein the administering is performed at least about: 1 time per day, 2 times per day, 3 times per day, 4 times per day, 5 times per day, or 6 times per day. 42. The method of claim 36, wherein the administering is performed for about: 1 day to about 8 days, 1 week to about 5 weeks, 1 month to about 12 months, 1 year to about 3 years, 3 years to about 10 years, 10 years to about 50 years, 25 years to about 100 years, or about 50 years to about 130 years. 43. The method of claim 36, wherein the subject has joint pain, join inflammation, joint immobilization, joint deterioration, or any combination thereof. 44. The method of claim 43, wherein the subject was previously diagnosed with acute arthritis, chronic arthritis, or any combination thereof. 45. The method of claim 44, comprising the acute arthritis which comprises: an infection, gout, calcium pyrophosphate arthritis, bursitis, tendinitis, or any combination thereof. 46. The method of claim 44, comprising the chronic arthritis which comprises: rheumatoid arthritis, psoriatic arthritis, lupus, erythematosus, osteoarthritis, juvenile idiopathic arthritis, fibromyalgia, polymyalgia rheumatica, or any combination thereof. 47. The method of claim 36, wherein the subject is a human. 48. The method of claim 47, wherein the human is from about 1 day to about 10 months old, from about 9 months to about 24 months old, from about 1 year to about 8 years old, from about 5 years to about 25 years old, from about 20 years to about 50 years old, from about 40 years to about 80 years old, or from about 50 years to about 130 years old. 49. The method of claim 36, wherein the subject is an animal. 50. The method of claim 49, wherein the animal comprises a pet. 51. The method of claim 50, wherein the pet comprises a dog, a cat, a rodent, a horse, a goat, or a rabbit. 52. The method of claim 49, wherein the animal is from about 1 day to about 10 months old, from about 9 months to about 24 months old, from about 1 year to about 8 years old, from about 5 years to about 25 years old, or from about 20 years to about 50 years old. 53. A method of treating or preventing a disease comprising administering the composition of any one of claims 1-35 to a subject as a pharmaceutical composition in unit dose form. 54. The method of claim 53, wherein the disease comprises acute arthritis, chronic arthritis, or any combination thereof. 55. The method of claim 54, wherein the disease comprises acute arthritis which comprises: an infection, gout, calcium pyrophosphate arthritis, bursitis, tendinitis, or any combination thereof. 56. The method of claim 55, wherein the disease comprises chronic arthritis which comprises: rheumatoid arthritis, psoriatic arthritis, lupus, erythematosus, osteoarthritis, juvenile idiopathic arthritis, fibromyalgia, polymyalgia rheumatica, or any combination thereof. 57. The method of claim 53, wherein prior to treating, the subject has been diagnosed with acute arthritis, chronic arthritis, or any combination thereof. 58. The method of claim 53, further comprising diagnosing the subject as having acute arthritis, chronic arthritis, or any combination thereof. 59. The method of claim 58, wherein the diagnosis comprises a physical examination, a radiological image, a blood test, an antibody test, or any combination thereof. 60. The method of claim 59, comprising the radiological image which comprises: a computed tomography (CT) image, an X-Ray image, a magnetic resonance image (MRI), an ultrasound image, or any combination thereof. 61. The method of claim 53, further comprising administering a second therapy to the subject. 62. The method of claim 61, wherein the second therapy comprises acetaminophen, an opioid, a nonsteroidal anti-inflammatory drug, methotrexate, hydroxychloroquine, prednisone, cortisone, a biological response modifier, a salt thereof, or any combination thereof. 63. The method of claim 62, wherein the second therapy comprises the biological response modifier which comprises: abatacept, adalimumab, adalimumab-atto, anakinra, certolizumab pegol, etanercept, etanercept-szzs, golimumab, infliximab, infliximab-dyyb, rituximab, sarilumab, tocilizumab, a biologically active fragment of any of these, a salt of any of these, or any combination thereof. 64. The method of claim 62, wherein the second therapy comprises the nonsteroidal anti- inflammatory drug which comprises naproxen, ibuprofen, a salt of any of these, or any combination thereof. 65. The method of claim 53, wherein the composition further comprises an excipient, a diluent, a carrier, or any combination thereof. 66. The method of claim 53, wherein the administering is by oral ingestion, topical application, or inhalation. 67. The method of claim 66, comprising the oral ingestion which comprises oral ingestion of a food, a liquid, a gel, a capsule, a tablet, or any combination thereof. 68. The method of claim 66, comprising the topical application which comprises topical application of a lotion, a tincture, a balm, a cream, an oil, a gel, a butter, a liquid, a spray, an ointment, a paste, a jelly, or any combination thereof. 69. The method of claim 66, comprising the inhalation which comprises inhalation by a diffuser, an inhaler, a nebulizer or any combination thereof. 70. The method of claim 53, wherein the administering is performed at least about: 1 time per day, 2 times per day, 3 times per day, 4 times per day, 5 times per day, or 6 times per day. 71. The method of claim 53, wherein the administering is performed for about: 1 day to about 8 days, 1 week to about 5 weeks, 1 month to about 12 months, 1 year to about 3 years, 3 years to about 10 years, 10 years to about 50 years, 25 years to about 100 years, or about 50 years to about 130 years. 72. The method of claim 53, wherein the subject is a subject in need thereof. 73. The method of claim 53, wherein the subject is a human. 74. The method of claim 73, wherein the human is from about 1 day to about 10 months old, from about 9 months to about 24 months old, from about 1 year to about 8 years old, from about 5 years to about 25 years old, from about 20 years to about 50 years old, from about 40 years to about 80 years old, or from about 50 years to about 130 years old. 75. The method of claim 53, wherein the subject is an animal. 76. The method of claim 75, wherein the animal comprises a pet. 77. The method of claim 76, comprising the pet which comprises a dog, a cat, a rodent, a horse, a goat, or a rabbit. 78. The method of claim 75, wherein the animal is about 1 day to about 10 months old, from about 9 months to about 24 months old, from about 1 year to about 8 years old, from about 5 years to about 25 years old, or from about 20 years to about 50 years old. 79. A method of making a composition of any one of claim 1-35, comprising formulating the following into a composition: CBD, a flavanone or a salt thereof; and one or more of: a glucosamine, a salt thereof, a glycosaminoglycan, a salt thereof, a vitamin, a derivative thereof, a salt thereof, or methylsulfonylmethane (MSM). 80. A method of making a composition, comprising formulating the following into a composition: CBD, naringenin or a salt thereof, and one or more of eucalyptus oil or lemon grass oil. 81. The method of claim 80, further comprising formulating D-limonene, a salt thereof, vitamin C, a salt thereof, MSM, a hemp cream, or any combination thereof into the composition. 82. The method of claim 80, wherein the CBD is at least partially water soluble. 83. The method of any one of claims 80-82, wherein the composition is formulated as a cream or a lotion. 84. A method of making a composition, comprising formulating the following into a composition: a medium-chain triglyceride (MCT) oil, CBD, and naringenin or a salt thereof. 85. The method of claim 84, further comprising formulating shea butter, cocoa butter, bees wax, lemon grass oil, frankincense oil, eucalyptus oil, D-limonene or a salt thereof, MSM, vitamin C or a salt thereof, or any combination thereof into the composition. 86. The method of claim 84, further comprising formulating a flavor or a fragrance into the composition. 87. The method of claim 84, wherein the CBD is at least partially water soluble. 88. The method of any one of claims 84-87, further comprising formulating the composition as a balm or a tincture. 89. A kit comprising the composition of any one of claims 1-35, and a container. |
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[0040] In some embodiments, a composition herein can comprise at least a portion of a plant, an extract thereof or both. In some cases, at least a portion of a plant or an extract thereof can comprise a Chinese herbal remedy. In some instances, a portion of a plant can comprise: a leaf, a stem, a seed, a root, a flower, bark, a wood, a fruit, or any combination thereof. An extract of a plant can comprise an extract of: a leaf, a stem, a seed, a root, a flower, bark, a wood, a fruit, or any combination thereof. In some cases, at least a portion of a plant, an extract thereof, or a tincture thereof, can comprise Boswellia serrata, lemon grass, Borago officinalis, eucalyptus, bromelain capsaicin cat’s claw curcumin turmeric cinnamon evening primrose ginger garlic black pepper, willow bark, frankincense, ginkgo, green tea, flaxseed, pine bar, aloe vera, flax, burdock root, nettles, licorice, rose hips, St. John’s wort, Devil's claw, hemp, stinging nettle, thyme, thunder god vine, valerian root, or any combination thereof. [0041] In some embodiments, a composition herein can comprise an oil. In some cases, an oil can be an oil of a plant, an animal, or both. In some instances, an oil can be an essential oil. An essential oil can be a plant extract. In some cases, an oil can be a cooking oil. In some cases, an oil can comprise avocado oil, soybean oil, black currant oil, lemon grass oil, peppermint oil, lavender oil, sandalwood oil, bergamot oil, rose oil, chamomile oil, ylang-ylang oil, basil oil, turmeric oil, ginger oil, evening primrose oil, tea tree oil, jasmine oil, rosemary oil, eucalyptus oil, myrrh oil, orange oil, clary sage oil, helichrysum oil, black pepper oil, rose oil, frankincense oil, hemp oil, borage oil or any combination thereof. In some cases, an oil can comprise, fish oil, turtle oil, mink oil, medium-chain triglyceride (MCT) oil, olive oil, vegetable oil, coconut oil, pumpkin seed oil, walnut oil, grapeseed oil, peanut oil, ghee oil, sesame oil, flaxseed oil, sunflower seed oil, canola oil, poppy seed oil, almond oil, apricot kernel oil, jojoba oil, wheat germ oil, safflower oil or any combination thereof. [0042] In some embodiments, a composition herein can comprise a fatty acid. In some cases, a fatty acid can be a short chain fatty acid, a medium chain fatty acid, a long chain fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. A fatty acid can be a saturated fatty acid, an unsaturated fatty acid, a monounsaturated fatty acid, a polyunsaturated fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. In some cases, a fatty acid can comprise an omega-3 fatty acid, an omega-6 fatty acid, an omega-7 fatty acid, an omega-9 fatty acid, an ester of any of these, a salt of any of these, or any combination thereof. For example, an omega-3 fatty acid can comprise alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), stearidonic acid, docosapentaenoic acid, eicosatrienoic acid, eicosatetraenoic acid, heneicosapentaenoic, heneicosapentaenoic acid, tetracosapentaenoic acid, tetracosahexaenoic acid, an ester of any of these, a salt of any of these or any combination thereof. Omega-6 fatty acids can comprise linoleic acid, gamma-linolenic acid, calendic acid, eicosadienoic acid, dihomo-gamma-linolenic acid, arachidonic acid, docosadienoic acid, adrenic acid, osbond acid, tetracosatetraenoic acid, tetracosapentaenoic acid, an ester of any of these, or a salt of any of these, or any combination thereof. In some cases, Omega-9 fatty acids can comprise hypogeic acid, oleic acid, elaidic acid, gondoic acid, mead acid, erucic acid, nervonic acid, ximenic acid, an ester of any of these, a salt of any of these, or any combination thereof. In some cases, an omega-7 fatty acid can comprise palmitoleic acid, vaccenic acid, rumenic acid, paullinic acid or any combination thereof. In some instances, a fatty acid can be a stearic acid, lauric acid, myristic acid, palmitic acid, a hydroxy fatty acid, a prostaglandin, a derivative or any of these, an ester of any of these, a salt of any of these, or any combination thereof. [0043] A composition described herein can comprise a ceramide, a phospholipid, any combination thereof. In some instances, the phospholipid can be a saturated phospholipid, an unsaturated phospholipid, a monoacylphospholipid or any combination thereof. In some instances, the phospholipid can comprise a liposome. In some instances, the phospholipid can be phosphatidic acid (phosphatidate), phosphatidylethanolamine (cephalin), phosphatidylcholine (lecithin), phosphatidylserine, phosphoinositides, phosphatidylinositol, phosphatidylinositol phosphate, phosphatidylinositol bisphosphate, phosphatidylinositol trisphosphate, ceramide phosphorylcholine (sphingomyelin), ceramide phosphorylethanolamine (sphingomyelin), ceramide phosphoryl lipid, a derivative or any of these, or any combination thereof. [0044] In some embodiments, a composition described herein can comprise a sugar, a sweetening agent or any combination thereof. In some cases, a sugar can comprise granulated sugar, brown sugar, confectioners’ sugar, fruit sugar, baker’s special sugar, a sugar cube, cane sugar, pearl sugar, or any form of sugar. In some cases, a sugar can comprise a liquid sugar. A liquid sugar can comprise honey, a syrup, a corn syrup (e.g. high fructose corn syrup), glucose syrup, maple syrup, molasses, a nectar (e.g. agave nectar) or any combination thereof. In some cases, sweetening agent can comprise a sugar alcohol (e.g. sorbitol, xylitol, mannitol), aspartame, saccharin, aspartame, acesulfame potassium, sucralose, advantame, neotame, stevia, isomalt maltodextrin or any combination thereof. [0045] In some embodiments, a composition can comprise an inactive ingredient. In some cases an inactive ingredient can comprise beta-caryophyllene, beta-ocimene, caryophyllene oxide, caryophyllene, a terpinolene tincture, terpene oil, humulene, a cannabis plant wax, a nitrogenous compound, an amino acid or salt thereof, an aldehyde, lecithin, flour, chromium picolinate, an herb, a ketone, chocolate, pectin, citric acid, a glycoside, shortening, coffee, coffee beans, a spice, calcium ascorbate, vanilla, manganese proteinate, potassium bicarbonate, egg, carprofen, a pigment, milk, cranberry, a fruit, a berry, a vegetable, a pepper, ethanol, trisodium citrate, a peppercorn, a habanero, a jalapeno, chocolate liquor, cream, glucose sugar syrup, vanilla extract, sea salt, vanilla bean powder, sodium bicarbonate, sorbitol powder, salt, smoked salt, milk fat, milk cream powder, dried skim milk, sunflower lecithin, blueberries, white chocolate, FD&C dye and lake colors, blue 1, blue 2, red 40, yellow 5, yellow 6, green 3, titanium dioxide, Arabic gum, unsweeted chocolate, soy lecithin, butter, water, or any combination thereof. In some embodiments, a composition such as a balm or a lotion can comprise shea butter, cocoa butter, bees wax, mango butter, kokum butter, red cocoa butter, or any combination thereof. In some cases, a composition such as a cream can comprise hemp cream. [0046] In some embodiments, a composition described herein can comprise a flavor. In some cases, a flavor can be a natural flavor, a flavor can be an artificial flavor, or a combination thereof. In some instances, a flavor can comprise acai berry, almond, amaretto, anise, apple, apricot, banana, bacon, bavarian cream, berry cola, birch beer, black licorice, black cherry, black currant, black walnut, blackberry, blue raspberry, blueberry, bourbon, bubble gum, butter, butter almond, butter milk, butter pecan, butter rum, butter toffee, butterscotch, cake batter, candy corn, caramel, caramel apple, caramel cream, carrot cake, champagne, cheesecake, cherry, cherry blossom, cherry cola, cherry cream spice, chocolate, chocolate cake, chocolate mint, cinnamon, cinnamon roll, coconut, coffee, cola, cookie dough, cotton candy, cranberry, cream soda, creme de menthe, cucumber, dill pickle, doughnut, elderberry, egg nog, eucalyptus, flan, fenugreek, fruity cereal, fruit punch, fuzzy navel, ginger ale, ginger beer, ginger lime, gingerbread, gingersnap, grand mariner, graham cracker, grape, grapefruit, green onion, hazelnut, honey, horchata, huckleberry, irish cream, irish whiskey, kettle corn, key lime, kiwi, lemon, lemon bar, lemon custard, lemon lime, lemon meringue pie, lemonade, lime, long island tea, macadamia nut, malted milk, mango, mango orange pineapple, maple, margarita, marshmallow, melon, melon kiwi, mint, mixed berry, mocha, mocha irish cream, mojito, moscow mule, nutmeg, orange, orange brandy, orange cream, orange mandarin, orange mango, orange pineapple, papaya, passion fruit, peach, peanut, pear, pecan, pecan roll, peppermint, pina colada, pineapple, pink lemonade, pistachio, plantation punch, plum, pomegranate, prickly pear, pumpkin, pumpkin pie, punch, quinine, raspberry, raspberry ginger ale, rock and rye, root beer, rum, sarsaparilla, sassafras, smoke, sour, strawberry, strawberry kiwi, spice, spearmint, tangerine, tart lemon, tequila, toasted coconut, toffee, tonic, tropical punch, tutti frutti, vanilla, vanilla cream, watermelon, white chocolate, whipped cream, wild cherry cream, wintergreen, or any combination thereof. [0047] In some embodiments, a composition described herein can comprise a fragrance. In some cases, a fragrance can be a natural fragrance, an artificial fragrance or a combination thereof. In some cases, a fragrance can come from an essential oil or from a plant extract. In some cases, a fragrance can be a spice such as nutmag, can comprise a flavor or both. In some instances, the composition can comprise a fragrance, a paraben, a phthalate, an alcohol, or any combination thereof, for example less than about: 5%, 4%, 3%, 2%, 1%, 0.5%, or 0.1% with respect to a total weight or a total volume of a composition . In some instances, the fragrance can be a perfume, cologne, an aftershave, or any combination thereof. In some instances, the composition can be free from a fragrance, a paraben, a phthalate, an alcohol, or any combination thereof. [0048] In some cases, a composition herein does not comprise a color additive. In some cases, the composition can comprise a color additive. In some cases, the composition may contain an incidental ingredient such as a color additive in an insignificant level in the composition, for example less than about: 5%, 4%, 3%, 2%, 1%, 0.5%, or 0.1% with respect to a total weight or a total volume of a composition. In some cases, the incidental ingredient may have no technical/structural, functional or any combination thereof effect in the composition, e.g., no an active ingredient. [0049] In some cases, a cosmetic composition described herein can include an alpha hydroxy acid, a beta hydroxyl acid, diethanolamine (DEA), a talc or any combination thereof. In some instances, a beta hydroxyl acid can be salicylic acid, beta hydroxybutanoic acid, tropic acid, trethocanic acid, a salt thereof or any combination thereof. In some instances, the diethanolamine can comprise cocamide DEA, cocamide monoethanolamine (MEA), DEA-cetyl phosphate, DEA Oleth-3 phosphate, lauramide DEA, linoleamide MEA, myristamide DEA, oleamide DEA, stearamide MEA, TEA-lauryl sulfate, triethanolamine, a salt thereof, or any combination thereof. In some cases, a composition, such as a cosmetic, can comprise water, glycerol, saline, a flower extract, a mineral oil, a synthetic oil, a silicate, a calcium salt, a magnesium salt potassium chloride, lactic acid, a starch, a sugar alcohol, a cellulose, an activated charcoal, a glycerin, a butter, an amino acid, a paraffin, honey, a wax, an agar, calcium carbonate, a citric acid, tartaric acid, a steric acid, xanthan gum, benzoic acid, a polyethylene glycol, a silicon, derivatives thereof, salts thereof, or any combination thereof. In some cases, a composition disclosed herein can comprise a filler, a binder, a disintegrant, a coating, a sorbent, an anti-adherent, a lubricant, a glidant, an antioxidant, a surfactant, a solvent, a chelating agent, a viscosity imparting agent, a surface active agent a humectant or any combination thereof. [0050] In some cases, a composition disclosed herein can comprise a preservative. In some instances, the preservative can be an organic/natural compound, a synthetic compound or any combination thereof. In some instances, the preservative can be an antimicrobial, an antibacterial, an antifungal, an antiviral, an antiseptic, a detergent, or any combination thereof. In some cases, a cosmetic preservative can be a paraben, a formaldehyde releaser, an isothiazolinone, a phenoxyethanol, an organic acid, a quaternary ammonium compound, or any combination thereof. In some cases, a food preservative can comprise benzoates, nitrites, sulphites, sorbates or any combination thereof. [0051] In some cases, a composition disclosed herein can comprise a cosmetically appropriate ingredient. In some instances, the composition may be safe under labeled or customary conditions of use. In some instances, a packaged product comprising the composition can be properly labeled, and the use of the ingredient does not otherwise cause the cosmetic to be adulterated or misbranded. In some instances, the adulterated condition can include: any poisonous or deleterious substance that can injure a user; a filthy, putrid, or decomposed substance; a cosmetic that may have been prepared, packed or held under insanitary conditions; a container that can comprise poisonous or deleterious substance which may render the contents injurious to health; or any combination thereof. [0052] In some cases, a composition disclosed herein can comprise a dietary supplement appropriate ingredient. In some instances, the composition may be safe under labeled or customary conditions of use. In some instances, a packaged product comprising the composition can be properly labeled, and the use of the ingredient does not otherwise cause the dietary supplement to be adulterated or misbranded. In some instances, the supplement can be manufactured according to good manufacturing practice (cGMP) and labeling regulations. [0053] In some cases, a composition disclosed herein can be aseptic. In some cases, the composition can comprise resident microbes. The microbes can be viruses, bacteria, eukaryotic cells or any combination thereof. In some instances, the microbes may not be pathogenic. In some instances, the composition can comprise a bacterium or bacteria at a concentration of less than about: 10 colony forming units (CFU)/gram (g), 50 CFU/g 100 CFU/g, 150 CFU/g, 200 CFU/g, 300 CFU/g, 400 CFU/g, 500 CFU/g, 600 CFU/g, 700 CFU/g, 800 CFU/g, 900 CFU/g, or 1000 CFU/g. In some cases, the composition can comprise bacteria at a concentration of about: 10 CFU/g to about 1000 CFU/g, 10 CFU/g to about 50 CFU/g, 20 CFU/g to about 100 CFU/g, 50 CFU/g to about 200 CFU/g, 100 CFU/g to about 250 CFU/g, 200 CFU/g to about 500 CFU/g, 500 CFU/g to about 700CFU/g, or 600 CFU/g to about 1000 CFU/g. In some instances, the composition may be substantially free or free of: Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Pseudomonas species, Klebsiella pneumoniae, or any combination thereof. [0054] In some cases, a composition disclosed herein may not contain a heavy metal or toxic ingredients such as lead, bithionol, chlorofluorocarbon propellants, nitrosamines, chloroform, halogenated salicylanilides, hexachlorophene, mercury compounds, 1,4-dioxane, methylene chloride, prohibited cattle materials, sunscreen compounds, vinyl chloride, zirconium-containing complexes, or any combination thereof. In some instances, the prohibited cattle materials can comprise the brain, skull, eyes, trigeminal ganglia, spinal cord, vertebral column, dorsal root ganglia, tonsils, distal ileum of the small intestine or any combination thereof. In some instances, the composition may comprise lead at levels of 10 (parts per million) ppm or less. [0055] In some cases, a kit can comprise a composition disclosed herein. In some cases, a kit can comprise a container. In some instances, a container can be plastic, glass, metal or any combination thereof. Methods of Formulating Compositions [0056] In some embodiments, a composition disclosed herein can be formulated as a pharmaceutical composition or a supplement composition. In some cases, a composition can comprise an excipient, a diluent, a carrier or any combination thereof. In some cases, the compositions can be made by mixing a composition described herein, and a pharmaceutically acceptable excipient. An excipient can be an excipient described in the Handbook of Pharmaceutical Excipients, American Pharmaceutical Association (1986). [0057] Non-limiting examples of suitable excipients can include a buffering agent, a preservative, a stabilizer, a binder, a compaction agent, a lubricant, a chelator, a dispersion enhancer, a disintegration agent, a flavoring agent, a sweetener, a coloring agent or any combination thereof. In some instances, the excipient comprising one or more of cellulose, disodium hydrogen phosphate, hydroxypropyl cellulose, hypromellose, lactose, mannitol, or sodium lauryl sulfate. In some instances, the compositions further comprise glyceryl monostearate 40-50, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer type C, polysorbate 80, sugar spheres, talc, or triethyl citrate. In some instances, a composition can further comprise carnauba wax, crospovidone, diacetylated monoglycerides, ethylcellulose, hydroxypropyl cellulose, hypromellose phthalate, magnesium stearate, mannitol, sodium hydroxide, sodium stearyl fumarate, talc, titanium dioxide, or yellow ferric oxide. In some instances, a composition can further comprise calcium stearate, crospovidone, hydroxypropyl methylcellulose, iron oxide, mannitol, methacrylic acid copolymer, polysorbate 80, povidone, propylene glycol, sodium carbonate, sodium lauryl sulfate, titanium dioxide, and triethyl citrate. Examples of carriers for the composition include any degradable, partially degradable or non-degradable and generally biocompatible polymer, e.g., polystirex, polypropylene, polyethylene, polacrilex, poly-lactic acid (PLA), polyglycolic acid (PGA) and/or poly-lactic polyglycolic acid (PGLA), e.g., in the form or a liquid, matrix, or bead. In some instances, a binder can comprise starches, pregelatinized starches, gelatin, polyvinylpyrolidone, cellulose, methylcellulose, sodium carboxymethylcellulose, ethylcellulose, polyacrylamides, polyvinyloxoazolidone, polyvinylalcohols, C 12 -C 18 fatty acid alcohol, polyethylene glycol, polyols, saccharides, oligosaccharides or any combination thereof. [0058] In, some embodiments an excipient can comprise a buffering agent. Non-limiting examples of suitable buffering agents can include sodium citrate, magnesium carbonate, magnesium bicarbonate, calcium carbonate, and calcium bicarbonate. As a buffering agent, sodium bicarbonate, potassium bicarbonate, magnesium hydroxide, magnesium lactate, magnesium gluconate, aluminium hydroxide, sodium citrate, sodium tartrate, sodium acetate, sodium carbonate, sodium polyphosphate, potassium polyphosphate, sodium pyrophosphate, potassium pyrophosphate, disodium hydrogen phosphate, dipotassium hydrogen phosphate, trisodium phosphate, tripotassium phosphate, potassium metaphosphate, magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium silicate, calcium acetate, calcium glycerophosphate, calcium chloride, calcium hydroxide and other calcium salts or combinations thereof can be used in a pharmaceutical formulation. [0059] In some embodiments, a pharmaceutical composition can comprise a diluent. Non- limiting examples of diluents can include water, glycerol, methanol, ethanol, and other similar biocompatible diluents. In some cases, a diluent can be an aqueous acid such as acetic acid, citric acid, maleic acid, hydrochloric acid, phosphoric acid, nitric acid, sulfuric acid, or similar. In other cases, a diluent can be selected from a group comprising alkaline metal carbonates such as calcium carbonate; alkaline metal phosphates such as calcium phosphate; alkaline metal sulphates such as calcium sulphate; cellulose derivatives such as cellulose, microcrystalline cellulose, cellulose acetate; magnesium oxide, dextrin, fructose, dextrose, glyceryl palmitostearate, lactitol, choline, lactose, maltose, mannitol, simethicone, sorbitol, starch, pregelatinized starch, talc, xylitol and/or anhydrates, hydrates and/or pharmaceutically acceptable derivatives thereof or combinations thereof. [0060] In some embodiments, a salt can include, but are not limited to, metal salts such as sodium salt, potassium salt, cesium salt and the like; alkaline earth metals such as calcium salt, magnesium salt and the like; organic amine salts such as triethylamine salt, pyridine salt, picoline salt, ethanolamine salt, triethanolamine salt, dicyclohexylamine salt, N, N'- dibenzylethylenediamine salt and the like; inorganic acid salts such as hydrochloride, hydrobromide, phosphate, sulphate and the like; organic acid salts such as citrate, lactate, tartrate, maleate, fumarate, mandelate, acetate, dichloroacetate, trifluoroacetate, oxalate, formate and the like; sulfonates such as methanesulfonate, benzenesulfonate, p-toluenesulfonate and the like; and amino acid salts such as arginate, asparginate, glutamate and the like. In some cases, a salt can comprise a pharmaceutically acceptable salt. In some instances, a salt of a polypeptide or derivative thereof or a compound can be a Zwitterionic salt. [0061] In some embodiments, compositions disclosed herein can be in unit dose forms or multiple dose forms. For example, a pharmaceutical composition or a supplemental composition described herein can be in unit dose form. Unit dose forms, as used herein, refer to physically discrete units suitable for administration to human or non-human subjects (e.g. pets) and packaged individually. Each unit dose can contain a predetermined quantity of an active ingredient(s) that may be sufficient to produce the desired therapeutic effect or to supplement a diet, in association with pharmaceutical carriers, diluents, excipients or any combination thereof. Examples of unit dose forms can include, ampules, syringes, and individually packaged tablets and capsules. In some cases, a unit dose form can be comprised in a food, for example, a chocolate supplement. In some instances, unit-dosage forms can be administered in fractions or multiples thereof. A multiple dose form can be a plurality of identical unit dose forms packaged in a single container, which can be administered in segregated a unit dose form. Examples of a multiple dose form can include vials, bottles of tablets or capsules, bottles of gummies, or bottles of pints or gallons. In some instances, a multiple dose form can comprise different pharmaceutically active agents. In some cases, a unit dose form can be a serving. In some cases, a multiple dose form can have more than about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, 100 or 200 servings. In some cases, a multiple dose form can have less than about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, 100 or 200 servings. In some cases, a multiple dose form can have from about: 1 serving to about 200 servings, 1 serving to about 20 serving, 5 serving to about 50 servings, 10 servings to about 100 serving, or about 30 serving to about 150 servings. Methods of Use [0062] In some embodiments, disclosed herein can be a method, comprising administering a composition disclosed herein to a subject (e.g., a human or a pet) in need thereof. In some instances, the method can treat or prevent a disease in the subject. In some instances, the method can ameliorate a condition of the subject’ arthritis. In some instances, a method described herein can comprise administering a composition described herein as a dietary supplement. In some cases, a method described herein can comprise administering a composition herein as a cosmetic. [0063] In some embodiments, disclosed herein can be a method for improving, maintaining, or supplementing joint health. In some instances, the methods can be used to treat arthritis. In some instances, the disease or condition can be chronic arthritis, acute arthritis or both. In some instances, the method can reduce the symptoms of arthritis such as joint stiffness, a tender joint, locking of a joint, a warm joint, a swollen joint, redness of a joint, fatigue, gland swelling, or any combination thereof. In some instances, a method can prevent, reduce or eliminate the severity of an arthritic symptom. [0064] Administration disclosed herein to an area in need of treatment or therapy can be achieved by, for example and not by way of limitation, oral administration, topical administration, intravenous administration, inhalation administration, or any combination thereof. In some cases, delivery can include injection, catheterization, gastrostomy tube administration, intraosseous administration, ocular administration, otic administration, transdermal administration, oral administration, rectal administration, nasal administration, intravaginal administration, intracavernous administration, transurethral administration, sublingual administration, or a combination thereof. Delivery can include direct application to the affect tissue or region of the body. Delivery can include a parenchymal injection, an intra- thecal injection, an intra-ventricular injection, or an intra-cisternal injection. A composition provided herein can be administered by any method. A method of administration can be by joint injection, intraarterial injection, intracisternal injection, intramuscular injection, intraparenchymal injection, intraperitoneal injection, intraspinal injection, intrathecal injection, intravenous injection, intraventricular injection, stereotactic injection, subcutaneous injection, epidural, or any combination thereof. Delivery can include parenteral administration (including intravenous, subcutaneous, intrathecal, intraperitoneal, intramuscular, intravascular or infusion administration). In some embodiments, delivery can comprise a nanoparticle, a liposome, an exosome, an extracellular vesicle, an implant, or a combination thereof. In some cases, delivery can be from a device. In some instances, delivery can be administered by a pump, an infusion pump or a combination thereof. In some cases, delivery can be by an enema, an eye drop, a nasal spray, an ear drop, or any combination thereof. [0065] In some cases, administering can be oral ingestion. Oral ingestion delivery can comprise a tea, an elixir, a food, a drink, a syrup, a liquid, a gel, a capsule, a tablet, an oil, a tincture, or any combination thereof. In some cases, a food can be a medical food. In some cases, a medical food can comprise a capsule, a gummy, a candy, a chocolate, a beverage, a food, a liquid, an oil, a syrup or any combination thereof. In some cases, a dietary supplement can be administered by oral injection. In some cases, delivery can include a gummy (e.g. a carrageenan gummy). In some instances, a food can comprise a candy. In some instances, a food can comprise a chocolate. For example, a candy can comprise a gummy, a fruit candy drop, a sea salt caramel, a cookie, a cake, a brownie, a dessert, a caramel, a sucker, a hard candy, or any combination thereof. In some cases, a chocolate can comprise blueberry chocolate, a cranberry chocolate, a chocolate bar, an orange chocolate, a mint chocolate, a raspberry chocolate, a strawberry chocolate, a peanut butter cup, a fruit flavored chocolate, a citrus flavored chocolate, a fruit covered chocolate, a chocolate covered fruit, a pepper covered chocolate (e.g. habanero chocolate), a chocolate caramel, a coffee bean chocolate, a chocolate caramel cup, a chocolate caramel, a chocolate bar flow, a chocolate candy bar, a nut covered chocolate, or any combination thereof. In some cases, a food can be a granola bar, a snack, a cheese, a chip, or any combination thereof. In some cases, a food can comprise a drink, a beverage, a liquid, a syrup, or any combination thereof. In some cases, delivery can be a capsule or a tablet. [0066] In some instances, a capsule can comprise hydroxymethylcellulose. In some cases, a capsule can comprise a gelatin, hydroxypropylmethyl cellulose, pullulan, or any combination thereof. In some cases, capsules can comprise a coating, for example, an enteric coating. In some cases, a capsule can comprise a vegetarian product or a vegan product such as a hypromellose capsule. In some cases, a capsule size can comprise 000, 00, 0, 1, 2, 3, 4, 5, or any size. In some instances, the density of the capsules can be greater than about: 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, or 0.99 grams per milliliter (g/mL). In some cases, the density of the capsules can be less than: 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, or 0.99 g/mL. In some cases, the density of the capsules can be from about 0.01 g/ml to about 0.99 g/mL, from about 0.1 g/ml to about 0.9 g/mL, from about 0.4 g/ml to about 0.7 g/mL or from about 0.8 g/ml to about 0.9 g/mL. In some cases, delivery can comprise inhalation by an inhaler, a diffuser, a nebulizer, a vaporizer or a combination thereof. [0067] In some cases, delivery can include topical application (topical administration). For example, delivery can include topical application of: a lotion, a solution, an emulsion, a cream, a balm, an oil, a paste, a stick, an aerosol, a foam, a jelly, a foam, a mask, a pad, a powder, a solid, a tincture, a butter, a patch, a gel, a spray, a drip, a liquid formulation, an ointment or any combination thereof. In some cases, topical application can comprise administering to an external surface, such as a skin. In some cases, topical application can comprise applying a cosmetic. In some instances, the composition can be applied by pouring, sprinkling, spraying, rubbing, introduced onto, or otherwise. In some instances, topical administration can be administered directly to the site of the condition. [0068] In some instances, a subject can administer the composition in the absence of supervision. In some cases, a human can administer the composition to the subject. For example, an owner can administer a composition described herein to a pet. In some instances, a subject can administer the composition under the supervision of a medical professional (e.g., a physician, nurse, physician’s assistant, orderly, hospice worker, etc.). In some cases, a medical professional can administer the composition. In some cases, a cosmetic professional can administer the composition. In some cases, an animal professional (e.g. a veterinarian, a veterinary assistant, a zookeeper, etc.) can administer the composition. [0069] Administration or application of a composition disclosed herein can be performed for a duration of at least about at least about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 150, 200, 300, 400, 500, 600, 700, 800, 900, 1000 days consecutive or nonconsecutive days. In some cases, the composition can be administered for life. In some cases, administration or application of the composition described herein can be from about 1 to about 30 days, from about 1 to about 60 days, from about 1 to about 90 days, from about 1 to about 300 days, from about 1 to about 3000 days, from about 30 day to about 90 days, from about 60 days to about 900 days, from about 30 days to about 900 days, or from about 90 days to about 1500 days. In some cases, administration or application of the composition described herein can be from about: 1 week to about 5 weeks, 1 month to about 12 months, 1 year to about 3 years, 2 years to about 8 years, 3 years to about 10 years, 10 years to about 50 years, 15 years to about 40 years, 25 years to about 100 years, 30 years to about 75 years, 60 years to about 110 years, or about 50 years to about 130 years. [0070] Administration or application of a composition disclosed herein can be performed for a duration of at least about: 1 week, at least about 1 month, at least about 1 year, at least about 2 years, at least about 3 years, at least about 4 years, at least about 5 years, at least about 6 years, at least about 7 years, at least about 8 years, at least about 9 years, at least about 10 years, at least about 15 years, at least about 20 years, or for life. Administration can be performed repeatedly over a lifetime of a subject, such as once a day, once a week, or once a month for the lifetime of a subject. Administration can be performed repeatedly over a substantial portion of a subject’s life, such as once a day, once a week, or once a month for at least about: 1 year, 5 years, 10 years, 15 years, 20 years, 25 years, 30 years, or more. [0071] Administration or application of composition disclosed herein can be performed at least about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, or 24 times a in a 24-hour period. In some instances, administration of a capsule, a tablet, a gummy, a chocolate, or a candy can comprise administration of more than one capsules, tablets, gummies, chocolates or candies. In some cases, administration or application of a composition disclosed herein can be performed continuously throughout a 24-hour period. In some cases, administration or application of composition disclosed herein can be performed at least about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, or 21 times a week. In some cases, administration or application of a composition disclosed herein can be performed at least about: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, or more times a month. In some cases, a composition can be administered as a single dose or as divided doses. In some cases, the compositions described herein can be administered at a first time point and a second time point. In some cases, a composition can be administered such that a first administration can be administered before the other with a difference in administration time of about: 1 hour, 2 hours, 4 hours, 8 hours, 12 hours, 16 hours, 20 hours, 1 day, 2 days, 4 days, 7 days, 2 weeks, 4 weeks, 2 months, 3 months, 4 months, 5 months, 6 months, 7 months, 8 months, 9 months, 10 months, 11 months, 1 year or more. [0072] In some embodiments, treatment for arthritis can comprise administering a second therapy. A second therapy can comprise acetaminophen, an opioid, a nonsteroidal anti- inflammatory drug, methotrexate, hydroxychloroquine, doxycycline, prednisone, cortisone, a biological response modifier, a salt thereof, or any combination thereof. In some cases, a second therapy can comprise a steroid. A second therapy can comprise a corticosteroid, such as a cortisone joint injection. In some cases, a second therapy can comprise biological response modifier. A biological modified can include abatacept, adalimumab, adalimumab-atto, anakinra, azathioprine, certolizumab pegol, etanercept, etanercept-szzs, hydroxychloroquine, leflunomide, methotrexate, sulfasalazine, tofacitinib, golimumab, infliximab, infliximab-dyyb, rituximab, sarilumab, tocilizumab, a biologically active fragment of any of these, a salt of any of these, or any combination thereof. In some cases, a second therapy can comprise a biosimilar. In some instances, a second therapy can include hyaluronic acid. In some cases, a second therapy can be an immunosuppressive drug, an antibiotic or both. In some cases, a second therapy can comprise a nonsteroidal anti-inflammatory drug (NSAID) such as naproxen, ibuprofen, aspirin, celecoxib, diclofenac, diflunisal, etodolac, indomethacin, ketoprofen, ketorolac, nabumetone, oxaprozin, piroxicam, salsalate, a salt of any of these, or any combination thereof. In some instances, a second therapy can comprise occupational therapy for example, occupational therapy can comprise adding braces or supports to protect one or more joints. In some cases, a second therapy can comprise exercise, altered diet and nutritional intake or any combination thereof. A second therapy can comprise joint aspiration to remove fluid from a joint. In some instances, a second therapy can comprise surgery. For example, a surgery can comprise a synovectomy to remove damaged connective tissue in a joint cavity, a joint replacement (e.g. knee or hip joint) or any combination thereof. [0073] In some embodiments, a subject may have been diagnosed with arthritis. In some cases, a subject may have diagnosed prior to treatment. In some cases, a method described herein can further comprise diagnosing a subject. In some cases, diagnosis may comprise diagnosis with acute arthritis, chronic arthritis, or both. In some cases, diagnosis can comprise a physical examination, a radiological image, a blood test, an antibody test or any combination thereof. A radiological image can comprise a computed tomography (CT) image, an X-Ray image, a magnetic resonance image (MRI), an ultrasound image, a bone scan or any combination thereof. A blood test can comprise measuring rheumatoid factor, anti-cyclic citrullinated peptide, erythrocyte sedimentation rate, C-reactive protein, antinuclear antibody, HLA-B27, complete blood count, creatine kinase, complement, cryoglobulins, or any combination thereof. In some cases, a physical examination can comprise an examination of joints for example, assessing the pain in joints. In some instances, a physical examination can comprise examination of one or more symptoms. In some cases, a diagnosis can comprise measuring a level compared to a standard level. For example, determining the level of rheumatoid factor or determining the level of joint damage on an X-Ray. EXAMPLES Example 1. Making a capsule composition comprising CBD, naringenin, glucosamine sulfate, chondroitin sulfate, and methylsulfonylmethane. [0074] A mixture comprising CBD, naringenin, glucosamine sulfate, chondroitin sulfate, and methylsulfonylmethane (MSM) were contacted together as a dry mix. The composition comprises: 10 mg CBD, 10 mg naringenin, 600 mg glucosamine sulfate, 300 mg chondroitin sulfate, and 375 mg MSM. The composition was added to a 00 size capsule at a density of about 0.8-0.9 g/ml. Example 2. Making a capsule composition comprising CBD, naringenin, calcium ascorbate, and MSM. [0075] A mixture comprising CBD, naringenin, calcium ascorbate, and methylsulfonylmethane (MSM) were contacted together as a dry mix. The composition comprises: 40 mg CBD, 10 mg naringenin, 500 mg calcium ascorbate, and 750 mg MSM. The composition was added to a 00 size capsule at a density of about 0.85-0.9 g/ml. Example 3. Making a capsule composition comprising CBD, naringenin, glucosamine sulfate, and MSM. [0076] A mixture comprising CBD, naringenin, glucosamine sulfate, and methylsulfonylmethane (MSM) were contacted together as a dry mix. The composition comprises: 20 mg CBD, 10 mg naringenin, 600 mg glucosamine sulfate, and 700 mg MSM. The composition was added to a 00 size capsule at a density of about 0.85-0.9 g/ml. Example 4. Making a capsule composition comprising CBD, naringenin, chondroitin sulfate, and MSM. [0077] A mixture comprising CBD, naringenin, chondroitin sulfate, and methylsulfonylmethane (MSM) is contacted together as a dry mix. The composition comprises: 10 mg CBD, 10 mg naringenin, 500 mg chondroitin sulfate, and 750 mg MSM. The composition is added to a 00 size capsule at a density of about 0.85-0.9 g/ml. The composition described is administered as two capsules three times daily to a human subject and to a canine subject. The human subject and the canine subject have increased joint mobility after administration compared to joint mobility prior to treatment. Example 5. Making a CBD balm [0078] A mixture comprising shea butter, cocoa butter, bees wax, MCT oil, lemon grass oil, frankincense oil, eucalyptus oil, naringenin and water-soluble CBD is made into a balm. The composition comprises: 12.37 g shea butter, 12.37 g cocoa butter, 3.32 g bees wax, 12 mL MCT Oil, 0.72 mL lemon grass oil, 0.72 mL frankincense oil .72 ml, 0.72 mL eucalyptus oil.1.0 g of naringenin and 1.5 g CBD. The ingredients are mixed together in large metal pot for 15 to 20 minutes on hot plate at 67 degrees Celsius. Once the ingredients have melted and been mixed for 3 to 5 minutes, the composition is poured into jars. The balm is directly applied to a joint to help improve mobility and decrease swelling. Example 6. Making a CBD tincture [0079] A mixture comprising MCT oil, naringenin and CBD is made into a tincture. The composition comprises: 30 mL MCT Oil, 1.0 g of naringenin, 0.24 mL of mint flavor, and 3 g CBD. The ingredients are mixed together in a 3000 mL beaker. The solution is placed in a double boiler until the CBD is fully emulsified. Then the solution is placed on a hot plate and stirred until the solution is emulsified. The solution is aliquoted into 5 mL oil bottles. The tincture is applied to a finger joint to supplement joint health. Example 7. Making a CBD, naringenin, D-limonene, and Vitamin C infused chocolate bar flow wrap [0080] A mixture comprising liquid CBD, Naringenin, Vitamin C (calcium ascorbate) and D- limonene is added to a recipe for a chocolate bar flow wrap. The chocolate bar flow wrap is a chocolate bar with a caramel center. The chocolate bar flow wrap comprises: 25 mg of CBD, 10 mg of naringenin, 50 mg of Vitamin C, and 125 mcg of D-limonene. The CBD, Naringenin, Vitamin C (calcium ascorbate) and D-limonene are mixed together and added to the dark chocolate bar ingredients (e.g. dark chocolate, cream, glucose syrup, sorbitol powder, sunflower lecithin, cocoa butter, naturally smoked salt). The combined ingredients are mixed completely under low heat until homogenized and poured into a chocolate bar mold that permits caramel to be added once the chocolate mixture is hardened. The chocolate bar flow wrap is ingested by a human subject to supplement the diet and maintain joint health. Example 8. Making a CBD, naringenin, D-limonene, and Vitamin C infused fruit candy drop [0081] A mixture comprising liquid CBD, Naringenin, Vitamin C (calcium ascorbate) and D- limonene is added to a recipe for a fruit candy drop. The fruit candy drop is a candy that is sweetened with isomalt. The fruit candy comprises: 10 mg of CBD, 10 mg of naringenin, 100 mg of Vitamin C, and 125 mcg of D-limonene. The CBD, Naringenin, Vitamin C (calcium ascorbate) and D-limonene are mixed together and added to the fruit candy drop ingredients (e.g. isomalt, water, citric acid, flavoring and coloring). The combined ingredients are mixed completely under low heat until homogenized and poured into a fruit candy drop mold. The fruit candy drop is ingested by a pet or a human to supplement the diet and maintain joint health. Example 9. Administering a composition [0082] The composition of example 1 or example 2 is administered as two capsules taken three times daily by a human subject and a canine subject. The human subject and the canine subject have decreased joint inflammation compared to the joint prior to treatment.