Title:
COMPOSITIONS COMPRISING CYCLOTIDES AND OTHER INSECTICIDAL PEPTIDES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/136442
Kind Code:
A3
Abstract:
The present invention relates to an insecticidal composition comprising: a. at least one cyclic peptide comprising an amino acid sequence of any of: SEQ ID NOs: 1, 2 or 6, or an amino acid sequence that is at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identical to any of SEQ ID NOs: 1, 2 or 6; and b. at least one second peptide comprising an amino acid sequence of any of SEQ ID NOs: 3 to 5, or an amino acid sequence that is at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identical to any of SEQ ID NOs: 3 to 5, or a variant of a peptide comprising an amino acid sequence of SEQ ID NO: 3, wherein the amino acid sequence has an amino acid variant on position N29, and which retains the biological activity of the peptide.
Inventors:
BENFATTI FIDES (CH)
BIGOT AURELIEN (CH)
CRAIK DAVID J (AU)
HUANG YEN-HUA (AU)
KAAS QUENTIN (AU)
SCHIEBLER MARK (CH)
WANG CONAN (AU)
BIGOT AURELIEN (CH)
CRAIK DAVID J (AU)
HUANG YEN-HUA (AU)
KAAS QUENTIN (AU)
SCHIEBLER MARK (CH)
WANG CONAN (AU)
Application Number:
PCT/EP2021/087104
Publication Date:
August 11, 2022
Filing Date:
December 21, 2021
Export Citation:
Assignee:
SYNGENTA CROP PROTECTION AG (CH)
International Classes:
C07K14/435; A01N63/50; C12N15/82
Domestic Patent References:
| WO2010039652A2 | 2010-04-08 |
Foreign References:
| US20150148288A1 | 2015-05-28 | |||
| US20200207818A1 | 2020-07-02 | |||
| US20200255482A1 | 2020-08-13 |
Other References:
VOLKER HERZIG ET AL: "The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin [omega]-Hexatoxin-Hv1a", TOXINS, vol. 7, no. 10, 1 October 2015 (2015-10-01), CH, pages 4366 - 4380, XP055678972, ISSN: 2072-6651, DOI: 10.3390/toxins7104366
Attorney, Agent or Firm:
HGF (NL)
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