COMPOSITIONS COMPRISING AN INTEGRIN INHIBITOR AND AGENTS WHICH INTERACT WITH A CHEMOKINE AND METHODS OF USE THEREOF

Title:

COMPOSITIONS COMPRISING AN INTEGRIN INHIBITOR AND AGENTS WHICH INTERACT WITH A CHEMOKINE AND METHODS OF USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2018/085574

Kind Code:

A3

Abstract:

The present disclosure provides methods of treating a patient comprising administering an agent which interacts with a chemokine such as G-CSF, plerixafor, or Gro-β and VLA-4 inhibitors. These methods may be used in the treatment of a condition which requires the collection of hematopoietic stem cells for transfusions or in chemotherapy.

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Inventors:

DIPERSIO JOHN F (US)
KARPOVA DARJA (US)

Application Number:

PCT/US2017/059770

Publication Date:

July 12, 2018

Filing Date:

November 02, 2017

Export Citation:

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Assignee:

UNIV WASHINGTON (US)
DIPERSIO JOHN F (US)
KARPOVA DARJA (US)

International Classes:

A61K31/395; A61K35/28; A61K38/19

Foreign References:

US20100003224A1	2010-01-07
US20150374736A1	2015-12-31
US20060035829A1	2006-02-16

Attorney, Agent or Firm:

ROBERTS, Brett J. et al. (US)

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