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Title:
COMPOSITIONS COMPRISING MINERALS, PROTEINS AND FATTY ACIDS FOR THE TREATMENT OF MASTITIS
Document Type and Number:
WIPO Patent Application WO/2020/043700
Kind Code:
A3
Abstract:
A mineral selected from the group consisting of iron, manganese and magnesium, or combination of two of more thereof; An n-3 fatty acid selected from the group consisting of docosahexaenoic acid (DHA) and 18:3 n-3 octadecatrienoic acid (alpha-linolenic acid); or a protein selected from the group consisting of alpha-lactalbumin, lactoferrin and albumin for use in treating or preventing mastitis in a subject.

Inventors:
SAMUEL TINU (CH)
SILVA ZOLEZZI IRMA (SG)
Application Number:
PCT/EP2019/072794
Publication Date:
April 09, 2020
Filing Date:
August 27, 2019
Export Citation:
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Assignee:
NESTLE SA (CH)
International Classes:
A61K33/04; A61K31/202; A61K31/355; A61K31/6615; A61K31/685; A61K33/26; A61K33/30; A61K33/32; A61K33/34; A61K38/00; A61K45/06; A61L2/00; A61P15/14; A61P29/00; A61P43/00
Domestic Patent References:
WO2007094000A22007-08-23
WO2004112776A22004-12-29
WO2007142542A22007-12-13
WO2016204169A12016-12-22
Foreign References:
CN104757317A2015-07-08
Other References:
DR MEE LAIN LING: "Iron-rich diet helps stave off mastitis | Richmond News", 15 November 2013 (2013-11-15), XP055548165, Retrieved from the Internet [retrieved on 20190128]
ANIRBAN GUHA ET AL: "Evaluation of Milk Trace Elements, Lactate Dehydrogenase, Alkaline Phosphatase and Aspartate Aminotransferase Activity of Subclinical Mastitis as and Indicator of Subclinical Mastitis in Riverine Buffalo (Bubalus bubalis)", ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES., vol. 25, no. 3, 1 March 2012 (2012-03-01), KR, pages 353 - 360, XP055548305, ISSN: 1011-2367, DOI: https://doi.org/10.5713/ajas.2011.11426
HE XUEXIU ET AL: "Docosahexaenoic acid attenuates LPS-stimulated inflammatory response by regulating the PPAR[gamma]/NF-[kappa]B pathways in primary bovine mammary epithelial cells", RESEARCH IN VETERINARY SCIENCE, BRITISH VETERINARY ASSOCIATION, LONDON, GB, vol. 112, 5 January 2017 (2017-01-05), pages 7 - 12, XP085046256, ISSN: 0034-5288, DOI: 10.1016/J.RVSC.2016.12.011
SEN LIN ET AL: "Mammary inflammatory gene expression was associated with reproductive stage and regulated by docosahexenoic acid: in vitro and in vivo studies", LIPIDS IN HEALTH AND DISEASE, vol. 15, no. 1, 1 December 2016 (2016-12-01), XP055671682, DOI: 10.1186/s12944-016-0386-1
TINU M SAMUEL: "P-80. SUBCLINICAL MASTITIS MODIFIES HUMAN MILK COMPOSITION: NEW INSIGHTS FROM A EUROPEAN COHORT", BREASTFEEDING MEDICINE, vol. 13, no. 7, 12 September 2018 (2018-09-12), US, pages A - 1, XP055548240, ISSN: 1556-8253, DOI: 10.1089/bfm.2018.29100.abstracts
Attorney, Agent or Firm:
GAGLIARDI, Tatiana (CH)
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