Title:
COMPOSITIONS AND METHODS COMPRISING A LIGAND OF CHEMERIN RECEPTOR
Document Type and Number:
WIPO Patent Application WO2005000875
Kind Code:
A3
Abstract:
The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screeing assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G-protein coupled receptor signaling.
Inventors:
WITTAMER VALERIE (BE)
COMMUNI DAVID (BE)
DETHEUX MICHEL (BE)
PARMENTIER MARC (BE)
LOISON CECILE (FR)
OOMS FR D RIC (BE)
COMMUNI DAVID (BE)
DETHEUX MICHEL (BE)
PARMENTIER MARC (BE)
LOISON CECILE (FR)
OOMS FR D RIC (BE)
Application Number:
PCT/EP2004/006945
Publication Date:
December 08, 2005
Filing Date:
June 25, 2004
Export Citation:
Assignee:
EUROSCREEN SA (BE)
WITTAMER VALERIE (BE)
COMMUNI DAVID (BE)
DETHEUX MICHEL (BE)
PARMENTIER MARC (BE)
LOISON CECILE (FR)
OOMS FR D RIC (BE)
WITTAMER VALERIE (BE)
COMMUNI DAVID (BE)
DETHEUX MICHEL (BE)
PARMENTIER MARC (BE)
LOISON CECILE (FR)
OOMS FR D RIC (BE)
International Classes:
C07K14/47; C07K14/575; C07K16/18; C07K16/28; G01N33/74; A61K38/00; (IPC1-7): C07K14/575; G01N33/68; C12N15/16; C12N15/63; A01K67/02; A61K38/22; A61P35/00
Foreign References:
| US20030096299A1 | 2003-05-22 | |||
| US20030022188A1 | 2003-01-30 |
Other References:
WITTAMER VALÉRIE ET AL: "Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids.", THE JOURNAL OF EXPERIMENTAL MEDICINE. 6 OCT 2003, vol. 198, no. 7, 6 October 2003 (2003-10-06), pages 977 - 985, XP002310262, ISSN: 0022-1007
WITTAMER VALÉRIE ET AL: "The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. 12 MAR 2004, vol. 279, no. 11, 12 March 2004 (2004-03-12), pages 9956 - 9962, XP002310263, ISSN: 0021-9258
WITTAMER VALÉRIE ET AL: "The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. 12 MAR 2004, vol. 279, no. 11, 12 March 2004 (2004-03-12), pages 9956 - 9962, XP002310263, ISSN: 0021-9258
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