COMPOSITIONS AND METHODS FOR DIAGNOSIS AND THERAPY OF MEDICAL CONDITIONS INVOLVING ANGIOGENESIS

Title:

COMPOSITIONS AND METHODS FOR DIAGNOSIS AND THERAPY OF MEDICAL CONDITIONS INVOLVING ANGIOGENESIS

Document Type and Number:

WIPO Patent Application WO2004004636

Kind Code:

A3

Abstract:

Compositions and methods are provided for diagnosis or therapy of medical conditions, or for tissue engineering, involving angiogenesis accompanied by the expression of E-selectin. More specifically, compounds are used that are selective for E-selectin binding with no significant ability to bind to P-selectin.

Inventors:

MAGNANI JOHN L (US)
PATTON JOHN T JR (US)

Application Number:

PCT/US2003/019429

Publication Date:

February 26, 2004

Filing Date:

June 19, 2003

Export Citation:

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Assignee:

GLYCOMIMETICS INC (US)
MAGNANI JOHN L (US)
PATTON JOHN T JR (US)

International Classes:

A61K49/00; (IPC1-7): A61K51/00; G01N33/00; C07H1/00; A01N43/04

Domestic Patent References:

WO1998006730A1

1998-02-19

Foreign References:

US6120751A

2000-09-19

Other References:

THOMA G. ET AL.: "A readily available, highly potent E-selectin antagonist", ANGEW. CHEM. INT. ED., vol. 40, no. 19, 2001, pages 3644 - 3647, XP002257743

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