Title:
COMPOSITIONS AND METHODS FOR IMAGING
Document Type and Number:
WIPO Patent Application WO/2019/227490
Kind Code:
A1
Abstract:
Provided are methods, imaging agents and kits for determination of the distribution and expression levels of an immune checkpoint ligand (such as PD-L1 or a PD-L1 like ligand) in an individual having a disease or condition. And Anti-PD-L1 antibody agents are also provided.
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Inventors:
CHEN LIEPING (CN)
LUO LIQUN (CN)
LIU QIANYONG (CN)
WEN ZHENGUO (CN)
YANG JIANGUO (CN)
LUO LIQUN (CN)
LIU QIANYONG (CN)
WEN ZHENGUO (CN)
YANG JIANGUO (CN)
Application Number:
PCT/CN2018/089672
Publication Date:
December 05, 2019
Filing Date:
June 01, 2018
Export Citation:
Assignee:
TAYU HUAXIA BIOTECH MEDICAL GROUP CO LTD (CN)
International Classes:
C07K16/28; G01N33/58
Domestic Patent References:
| WO2017148424A1 | 2017-09-08 | |||
| WO2017210302A1 | 2017-12-07 | |||
| WO2017059397A1 | 2017-04-06 | |||
| WO2006121168A1 | 2006-11-16 | |||
| WO2007005874A2 | 2007-01-11 |
Other References:
TROTTER, D.E.G. ET AL.: "IN VIVO IMAGING OF THE PROGRAMMED DEATH LIGAND 1 BY 18F PET", J. NUCL. MED., vol. 58, no. 11, 6 June 2017 (2017-06-06), pages 1852 - 1857, XP055658683
LI, DAN ET AL.: "Immuno-PET Imaging of 89Zr Labeled Anti-PD-Ll Domain Antibody", MOL. PHARMACEUTICS, vol. 15, no. 4, 5 March 2018 (2018-03-05), pages 1674 - 1681, XP055632621
LI, DAN ET AL.: "Immuno-PET Imaging of 89Zr Labeled Anti-PD-Ll Domain Antibody", MOL. PHARMACEUTICS, vol. 15, no. 4, 5 March 2018 (2018-03-05), pages 1674 - 1681, XP055632621
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
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