Title:
COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS
Document Type and Number:
WIPO Patent Application WO2002042329
Kind Code:
A3
Abstract:
The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered prostate tissue for treatment and research.
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Inventors:
SALCEDA SUSANA (US)
MACINA ROBERTO A (US)
RECIPON HERVE (US)
SUN YONGMING (US)
LIU CHENGHUA (US)
MACINA ROBERTO A (US)
RECIPON HERVE (US)
SUN YONGMING (US)
LIU CHENGHUA (US)
Application Number:
PCT/US2001/045177
Publication Date:
June 26, 2003
Filing Date:
November 20, 2001
Export Citation:
Assignee:
DIADEXUS INC (US)
SALCEDA SUSANA (US)
MACINA ROBERTO A (US)
RECIPON HERVE (US)
SUN YONGMING (US)
LIU CHENGHUA (US)
SALCEDA SUSANA (US)
MACINA ROBERTO A (US)
RECIPON HERVE (US)
SUN YONGMING (US)
LIU CHENGHUA (US)
International Classes:
C07K14/47; A61K38/00; A61K39/00; (IPC1-7): C07K14/47; C07K16/18; C12Q1/68; G01N33/577; A61K38/17; A61K31/7088
Domestic Patent References:
| WO1999060162A1 | 1999-11-25 | |||
| WO2000014234A1 | 2000-03-16 | |||
| WO1998035031A1 | 1998-08-13 | |||
| WO2000058470A1 | 2000-10-05 |
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