Title:
COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS
Document Type and Number:
WIPO Patent Application WO/2022/204043
Kind Code:
A8
Abstract:
Described herein are compositions, kits, and methods for potent delivery to a ceil of a subject. The cell can be of a particular cell type, such as a basal cell. In some cases, the cell can be a lung cell of a particular cell type. Also described herein are pharmaceutical compositions comprising a therapeutic or prophylactic agent assembled with a lipid composition. Tire lipid composition can comprise an ionizable cationic lipid, and a selective organ targeting lipid. The lipid composition can further comprise a phospholipid. Further described herein are high-potency intravenous dosage forms of a therapeutic or prophylactic agent formulated with a lipid composition.
Inventors:
TORRES MICHAEL (US)
SIEGWART DANIEL (US)
EBY JACKSON (US)
BHATTACHARJEE RUMPA (US)
WUSTMAN BRANDON (US)
KHARITONOV VLADIMIR (US)
CHENG QIANG (US)
WEI TUO (US)
SIEGWART DANIEL (US)
EBY JACKSON (US)
BHATTACHARJEE RUMPA (US)
WUSTMAN BRANDON (US)
KHARITONOV VLADIMIR (US)
CHENG QIANG (US)
WEI TUO (US)
Application Number:
PCT/US2022/021176
Publication Date:
November 03, 2022
Filing Date:
March 21, 2022
Export Citation:
Assignee:
UNIV TEXAS (US)
RECODE THERAPEUTICS INC (US)
RECODE THERAPEUTICS INC (US)
International Classes:
A61K9/51; A61K9/00; A61K47/24; A61K48/00
Attorney, Agent or Firm:
LONG, S., Reid (US)
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