Title:
COMPOSITIONS AND METHODS FOR TREATING RETINOPATHY
Document Type and Number:
WIPO Patent Application WO/2017/117512
Kind Code:
A3
Abstract:
Methods for treating retinopathy are provided and include administering an effective amount of a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject. The retinopathy can include diabetic retinopathy. Methods of decreasing angiogenesis in a retinal vasculature are also provided and include the step of administering, such as by intravitreous injection, a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof.
Inventors:
XIE ZIJIAN (US)
SHAPIRO JOSEPH I (US)
SHAPIRO JOSEPH I (US)
Application Number:
PCT/US2016/069451
Publication Date:
August 17, 2017
Filing Date:
December 30, 2016
Export Citation:
Assignee:
MARSHALL UNIV RES CORP (US)
International Classes:
A61K38/46; A61K38/10; A61P9/10; C07K14/47
Domestic Patent References:
| WO2006044916A2 | 2006-04-27 |
Foreign References:
| US20140187484A1 | 2014-07-03 |
Other References:
KOLLIAS ET AL.: "Diabetic Retinopathy Early Diagnosis And Effective Treatment", DEUTSCHES ARZTEBLATT INTERNATIONAL, vol. 107, 2010, pages 75 - 84, XP055406649
Attorney, Agent or Firm:
WRIGHT, Terry L. et al. (US)
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