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Title:
COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AND THE ASSOCIATED ABDOMINAL CRAMPING
Document Type and Number:
WIPO Patent Application WO/2015/001499
Kind Code:
A3
Abstract:
The invention relates to the compounds of formula (I) or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of irritable bowel syndrome and the associated abdominal cramping may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of coeliac disease, fructose malabsorption, mild infections, parasitic infections like giardiasis, several inflammatory bowel diseases, bile acid malabsorption, functional chronic constipation, small intestinal bacterial overgrowth, and chronic functional abdominal pain.

Inventors:
KANDULA MAHESH (IN)
Application Number:
PCT/IB2014/062798
Publication Date:
April 02, 2015
Filing Date:
July 02, 2014
Export Citation:
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Assignee:
KANDULA MAHESH (IN)
International Classes:
C07C31/22; C07C203/06; C08K5/103
Domestic Patent References:
WO2013167988A12013-11-14
WO2013016668A22013-01-31
Other References:
HARI ET AL.: "Discriminative Glycosylation of 3-(Aryloxy) propane-1, 2-diols by Choice of a Glycosyl Donor", SYNTHESIS, 2003, pages 2378 - 2384
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