Title:
COMPOSITIONS FOR REMOVING SENESCENT CELLS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/085787
Kind Code:
A1
Abstract:
The present disclosure provides a composition for removing senescent cells that is useful in senescent cell removal. The composition of the present invention induces the apoptosis of senescent cells and thus can be usefully applied to the amelioration, treatment, or prevention of various aging-associated diseases and disorders caused by senescent cells. In addition, the composition of the present invention can be usefully applied as pharmaceuticals, cosmetics, health functional foods, animal products, etc. in relation to aging-associated diseases and disorders caused by senescent cells.
Inventors:
KIM TAE KOOK (KR)
JANG HYUNG JU (KR)
CHOO KANG SIK (KR)
JANG HYUNG JU (KR)
CHOO KANG SIK (KR)
Application Number:
PCT/KR2022/017594
Publication Date:
May 19, 2023
Filing Date:
November 09, 2022
Export Citation:
Assignee:
LIFECEUTIX CO LTD (KR)
International Classes:
A61K31/714; A61K31/095; A61K31/28; A61K31/5025; A61K38/44; A61P17/00; A61P35/00; A61P43/00; G01N33/50
Domestic Patent References:
| WO2020095971A1 | 2020-05-14 |
Foreign References:
| US20200123607A1 | 2020-04-23 | |||
| KR20210100603A | 2021-08-17 | |||
| US20200121620A1 | 2020-04-23 | |||
| US20210275560A1 | 2021-09-09 | |||
| US20200371122A1 | 2020-11-26 |
Other References:
DAVALOS ALBERT R., KAWAHARA MISAKO, MALHOTRA GAUTAM K., SCHAUM NICHOLAS, HUANG JIAHAO, VED URVI, BEAUSEJOUR CHRISTIAN M., COPPE JE: "p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes", THE JOURNAL OF CELL BIOLOGY, THE ROCKEFELLER UNIVERSITY PRESS, US, vol. 201, no. 4, 13 May 2013 (2013-05-13), US , pages 613 - 629, XP093064964, ISSN: 0021-9525, DOI: 10.1083/jcb.201206006
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
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