Title:
COMPOSITIONS AND THERAPEUTIC METHODS FOR VIRAL INFECTION
Document Type and Number:
WIPO Patent Application WO2003015714
Kind Code:
A3
Abstract:
Methods for inhibiting viral propagation and treating viral infection are provided which include administering to cells infected with viruses a compound capable of inhibiting viral budding from the infected host cells.
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Inventors:
MORHAM SCOTT (US)
ZAVITZ KENTON (US)
HOBDEN ADRIAN (US)
ZAVITZ KENTON (US)
HOBDEN ADRIAN (US)
Application Number:
PCT/US2002/026681
Publication Date:
November 06, 2003
Filing Date:
August 21, 2002
Export Citation:
Assignee:
MYRIAD GENETICS INC (US)
MORHAM SCOTT (US)
ZAVITZ KENTON (US)
HOBDEN ADRIAN (US)
MORHAM SCOTT (US)
ZAVITZ KENTON (US)
HOBDEN ADRIAN (US)
International Classes:
A61K47/48; A61P31/12; C07K14/01; C07K14/02; C07K14/03; C07K14/035; C07K14/08; C07K14/145; C07K14/15; C07K14/16; C12N1/21; C12N5/22; C12N15/33; A61K38/00; A61K48/00; (IPC1-7): A61K38/00; A61K38/08; A61K38/10; A61K38/16; C07K4/02; C07K7/06; C07K7/08; C07K14/005; C12N15/33; C12N1/21
Foreign References:
| US6015787A | 2000-01-18 |
Other References:
HARTY ET AL.: "A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding", PROC. NATL. ACAD. SCI. USA, vol. 97, no. 25, December 2000 (2000-12-01), pages 13871 - 13876, XP002962275
IKEDA ET AL.: "PY motifs of epstein-barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins", JOURNAL OF VIROLOGY, vol. 75, no. 12, June 2001 (2001-06-01), pages 5711 - 5718, XP002962273
STRACK ET AL.: "A role for ubiquitin ligase recruitment in retrovirus release", PROC. NATL. ACAD. SCI. USA, vol. 97, no. 24, November 2000 (2000-11-01), pages 13063 - 13068, XP002962274
IKEDA ET AL.: "PY motifs of epstein-barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins", JOURNAL OF VIROLOGY, vol. 75, no. 12, June 2001 (2001-06-01), pages 5711 - 5718, XP002962273
STRACK ET AL.: "A role for ubiquitin ligase recruitment in retrovirus release", PROC. NATL. ACAD. SCI. USA, vol. 97, no. 24, November 2000 (2000-11-01), pages 13063 - 13068, XP002962274
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