Title:
COMPOUND HAVING BENZYLOXY ARYL ETHER STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/169371
Kind Code:
A1
Abstract:
Disclosed in the present invention are a compound having a benzyloxy aryl ether structure, and a preparation method therefor and the use thereof. The structure of the compound having the benzyloxy aryl ether structure is as represented by formula (I), and the definition of each substituent in the formula is as described in the description and the claims. The compound of the present invention can be used for preparing a small molecule inhibitor of PD1/PD-L1 interaction, which can be used for preventing and/or treating diseases related to PD1/PD-L1 interaction, especially cancers.
Inventors:
ZHAO YUJUN (CN)
ZHU DI (CN)
ZHOU FEILONG (CN)
YAN ZIQIN (CN)
LIU CHENGLONG (CN)
CENG ZIYU (CN)
CHENG YING (CN)
ZHU DI (CN)
ZHOU FEILONG (CN)
YAN ZIQIN (CN)
LIU CHENGLONG (CN)
CENG ZIYU (CN)
CHENG YING (CN)
Application Number:
PCT/CN2023/079898
Publication Date:
September 14, 2023
Filing Date:
March 06, 2023
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
UNIV FUDAN (CN)
UNIV FUDAN (CN)
International Classes:
C07D405/14; A61K31/423; A61K31/4375; A61K31/4439; A61K31/4709; A61P35/00; A61P35/02; A61P35/04; C07D413/06; C07D413/12; C07D413/14; C07D471/04
Foreign References:
| CN105705489A | 2016-06-22 | |||
| CN106536515A | 2017-03-22 | |||
| CN112028870A | 2020-12-04 | |||
| CN110799509A | 2020-02-14 | |||
| CN112812113A | 2021-05-18 |
Attorney, Agent or Firm:
XU & PARTNERS , LLC. (CN)
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