Title:
COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/080732
Kind Code:
A1
Abstract:
The present disclosure provides: a compound of a specific chemical structure, having excellent activity with respect to BTK degradation; or a pharmaceutically acceptable salt thereof. The present disclosure also provides a composition comprising the compound or pharmaceutically acceptable salts thereof. The present disclosure also provides are pharmaceutical use for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer) of the compound, the salt thereof, and the composition comprising same according to the present disclosure. The present disclosure also provides a method for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer), comprising administering, to a subject requiring treatment, an effective amount of the compound, the salt thereof, or the composition comprising same according to the present disclosure.
Inventors:
LEE SONG HEE (KR)
RYU JE HO (KR)
AHN JUNG MIN (KR)
MOON HEE JUNG (KR)
LEE HO HYUN (KR)
JANG MI YOUNG (KR)
YUN WHEE SAHNG (KR)
KIM YE EUN (KR)
YOO SUN MI (KR)
LIM YE SEUL (KR)
JEONG NA RAE (KR)
KIM SO HYUK (KR)
CHOI AE RAN (KR)
KIM HAN WOOL (KR)
RYU JE HO (KR)
AHN JUNG MIN (KR)
MOON HEE JUNG (KR)
LEE HO HYUN (KR)
JANG MI YOUNG (KR)
YUN WHEE SAHNG (KR)
KIM YE EUN (KR)
YOO SUN MI (KR)
LIM YE SEUL (KR)
JEONG NA RAE (KR)
KIM SO HYUK (KR)
CHOI AE RAN (KR)
KIM HAN WOOL (KR)
Application Number:
PCT/KR2022/017291
Publication Date:
May 11, 2023
Filing Date:
November 04, 2022
Export Citation:
Assignee:
UBIX THERAPEUTICS INC (KR)
International Classes:
C07D401/14; A61K31/506; C07D471/04
Domestic Patent References:
| WO2016201280A1 | 2016-12-15 | |||
| WO2020200291A1 | 2020-10-08 | |||
| WO2009137596A1 | 2009-11-12 | |||
| WO2008033834A1 | 2008-03-20 | |||
| WO2020069117A1 | 2020-04-02 |
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
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