COMPOUND HAVING KRAS G12D INHIBITORY EFFECT - HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD

Title:

COMPOUND HAVING KRAS G12D INHIBITORY EFFECT

Document Type and Number:

WIPO Patent Application WO/2024/027814

Kind Code:

A1

Abstract:

Disclosed are a compound as represented by formula (I) having a KRas G12D inhibitory effect, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, and the use thereof in the preparation of a drug for KRas G12D-related diseases.

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Inventors:

SUN WEI (CN)
ZHAI WENQIANG (CN)
WANG LING (CN)
DENG TAO (CN)
YE JIUYONG (CN)
YU XIANG (CN)
LIU DONGZHOU (CN)

Application Number:

PCT/CN2023/111146

Publication Date:

February 08, 2024

Filing Date:

August 04, 2023

Export Citation:

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Assignee:

HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN)

International Classes:

C07D487/08; A61K31/517; A61K31/519; A61K31/553; A61P35/00; C07D239/72; C07D498/16

Domestic Patent References:

WO2022105855A1	2022-05-27
WO2022105859A1	2022-05-27
WO2022188729A1	2022-09-15
WO2022268051A1	2022-12-29

Foreign References:

CN114615981A	2022-06-10
CN115141215A	2022-10-04

Attorney, Agent or Firm:

NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)

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