Title:
COMPOUND AND METAL COMPLEX
Document Type and Number:
WIPO Patent Application WO/2022/176961
Kind Code:
A1
Abstract:
Disclosed is a compound represented by formula (1). In formula (1), n represents an integer of 0-5. Q1, Q2, Q3, and Q4 represent a moiety selected from group A, a moiety selected from group B, a moiety represented by formula (C1), or the like. One or more of Q1, Q2, Q3, and Q4 is a moiety selected from group A, one or more of Q1, Q2, Q3, and Q4 is a moiety selected from group B, and three or more of Q1, Q2, Q3, and Q4 are moieties selected from group A, moieties selected from group B, or moieties represented by formula (C1). Group A is a group comprising moieties and the like represented by formula (A1). Group B is a group comprising moieties and the like represented by formula (B1). Z1, Z2, Z3, and Z4 represent a single bond or a divalent linking moiety. R represents a divalent linking moiety.
Inventors:
KOBAYASHI NORIFUMI (JP)
KOSHINO NOBUYOSHI (JP)
KOSHINO NOBUYOSHI (JP)
Application Number:
PCT/JP2022/006471
Publication Date:
August 25, 2022
Filing Date:
February 17, 2022
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C07D401/14; A61K51/04; C07F3/00; C07F5/00; C07F7/00
Domestic Patent References:
| WO2019232294A1 | 2019-12-05 | |||
| WO2015153772A2 | 2015-10-08 |
Foreign References:
| JPH01113349A | 1989-05-02 | |||
| JP2013515744A | 2013-05-09 | |||
| US5294717A | 1994-03-15 | |||
| JP2020515596A | 2020-05-28 |
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KHARADI, G.J.: "Thermal and Microbicidal Study of Coordination Polymers: Transition Metal with 8HQMIT Ligand", SYNTHESIS AND REACTIVITY IN INORGANIC, METAL-ORGANIC NANO-METAL CHEMISTRY, TAYLOR & FRANCIS INC., US, vol. 44, no. 7, 4 March 2014 (2014-03-04), US , pages 1001 - 1010, XP009539115, ISSN: 1553-3174, DOI: 10.1080/15533174.2013.797455
EDMONDS SCOTT, VOLPE ALESSIA, SHMEEDA HILARY, PARENTE-PEREIRA ANA C., RADIA RIYA, BAGUÑA-TORRES JULIA, SZANDA ISTVAN, SEVERIN GREG: "Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines", ACS NANO, AMERICAN CHEMICAL SOCIETY, US, vol. 10, no. 11, 22 November 2016 (2016-11-22), US , pages 10294 - 10307, XP055960212, ISSN: 1936-0851, DOI: 10.1021/acsnano.6b05935
SANDRA HESKAMP, RENé RAAVé, OTTO BOERMAN, MARK RIJPKEMA, VICTOR GONCALVES, FRANCK DENAT: "89 Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89 Zr Radiochemistry", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 28, no. 9, 20 September 2017 (2017-09-20), US , pages 2211 - 2223, XP055734862, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.7b00325
ERIC W. PRICE, CHRIS ORVIG: "Matching chelators to radiometals for radiopharmaceuticals", CHEMICAL SOCIETY REVIEWS, ROYAL SOCIETY OF CHEMISTRY, UK, vol. 43, no. 1, 7 January 2014 (2014-01-07), UK , pages 260 - 290, XP055397567, ISSN: 0306-0012, DOI: 10.1039/C3CS60304K
WANG XIAOZHU, JARAQUEMADA-PELÁEZ MARÍA DE GUADALUPE, CAO YANG, PAN JINHE, LIN KUO-SHYAN, PATRICK BRIAN O., ORVIG CHRIS: "H 2 hox: Dual-Channel Oxine-Derived Acyclic Chelating Ligand for 68 Ga Radiopharmaceuticals", INORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON , US, vol. 58, no. 4, 18 February 2019 (2019-02-18), Easton , US , pages 2275 - 2285, XP055960209, ISSN: 0020-1669, DOI: 10.1021/acs.inorgchem.8b01208
BRONSON R. TODD, BRADSHAW JERALD S., SAVAGE PAUL B., FUANGSWASDI SAOWARUX, LEE SANG CHUL, KRAKOWIAK KRZYSZTOF E., IZATT REED M.: "Bis-8-hydroxyquinoline-Armed Diazatrithia-15-crown-5 and Diazatrithia-16-crown-5 Ligands: Possible Fluorophoric Metal Ion Sensors", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 66, no. 14, 1 July 2001 (2001-07-01), pages 4752 - 4758, XP055960208, ISSN: 0022-3263, DOI: 10.1021/jo0017584
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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