COMPOUND FOR PREPARATION OF ANTIBODY-PAYLOAD CONJUGATE AND USE THEREOF

Title:

COMPOUND FOR PREPARATION OF ANTIBODY-PAYLOAD CONJUGATE AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2020/153774

Kind Code:

A1

Abstract:

The present application pertains to a novel linker for use in bioconjugation, containing two or more electrophilic carbon atoms of a carbonyl group, and a click chemistry functional group and, more specifically, to a linker through which a compound, a peptide, and/or a protein can be directly and/or indirectly linked by a substitution reaction to a desired target molecule, that is, a target molecule.

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Inventors:

CHUNG SANG JEON (KR)
KIM JU HWAN (KR)
LEE YOUNG GEUN (KR)
LEE TAE JIN (KR)
SEO JIN WOO (KR)

Application Number:

PCT/KR2020/001145

Publication Date:

July 30, 2020

Filing Date:

January 23, 2020

Export Citation:

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Assignee:

ABTIS CO LTD (KR)
RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR)

International Classes:

C07D207/46; A61K47/68; A61P35/00

Domestic Patent References:

WO2018213077A1	2018-11-22
WO2015122478A1	2015-08-20

Foreign References:

KR20140077207A	2014-06-23
KR20140017486A	2014-02-11
KR20160125515A	2016-10-31
KR20140114826A	2014-09-29

Other References: