Title:
COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/137463
Kind Code:
A1
Abstract:
A compound of formula (I) or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein M is a monovalent alkali metal, and a preparation method therefor, and use for treating CCR4-mediated diseases.
Inventors:
ZHAO HAI FENG (CN)
Application Number:
PCT/CN2019/071315
Publication Date:
July 18, 2019
Filing Date:
January 11, 2019
Export Citation:
Assignee:
MEDSPRING INTERNATIONAL LTD (CN)
International Classes:
C07D409/12; A61K31/416; A61P11/06; A61P11/08; A61P29/00; A61P37/08
Foreign References:
| CN102388039A | 2012-03-21 | |||
| CN201810032410A | 2018-01-12 | |||
| CN101370793A | 2009-02-18 | |||
| CN102388039A | 2012-03-21 |
Other References:
PROCOPIOU, P.A. ET AL.: "Lead Optimisation of the N1 Substituent of a Novel Series of Indazole Arylsulfonamides as CCR4 Antagonists and Identification of a Candidate for Clinical Investigation", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, no. 8, 7 March 2012 (2012-03-07), pages 2730 - 2733, XP055625236, ISSN: 0960-894X
CHRISTINE AP ET AL., J. BIOL. CHEM., vol. 270, no. 8, 1995, pages 19495 - 19500
SADATOSHI MAEDA ET AL., VETERINARY IMMUNOLOGY AND IMMUNOLOGY, vol. 90, 2002, pages 145 - 154
HAN WL ET AL., BIOCHEM J., vol. 357, 2001, pages 127 - 135
"Pharmacopoeia", 2010
See also references of EP 3738962A4
CHRISTINE AP ET AL., J. BIOL. CHEM., vol. 270, no. 8, 1995, pages 19495 - 19500
SADATOSHI MAEDA ET AL., VETERINARY IMMUNOLOGY AND IMMUNOLOGY, vol. 90, 2002, pages 145 - 154
HAN WL ET AL., BIOCHEM J., vol. 357, 2001, pages 127 - 135
"Pharmacopoeia", 2010
See also references of EP 3738962A4
Attorney, Agent or Firm:
BEIJING QIKUN INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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