Title:
COMPOUND AND USE OF SAME
Document Type and Number:
WIPO Patent Application WO/2023/210774
Kind Code:
A1
Abstract:
Provided is a compound that includes a peptide structure represented by formula (p1) or (p2). Also provided is a method for producing a droplet using the compound. Xa is an amino acid residue having a hydrophilic side chain. Xb is an amino acid residue having a side chain represented by formula (b1). Xc and Xd each independently an amino acid residue or glycine residue having a hydrophobic side chain. n is an integer between 1 and 3. Ar1 is an optionally substituted aryl group or heteroaryl group. Ar2 is an optionally substituted arylene group or heteroarylene group. Formula (p1): XaXb(XaXc)nXaXdXa. Formula (p2): XaXd(XaXc)nXaXbXa.
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Inventors:
MURAOKA TAKAHIRO (JP)
UCHIDA NORIYUKI (JP)
FU JAKUEI (JP)
HIGUCHI GENKI (JP)
UCHIDA NORIYUKI (JP)
FU JAKUEI (JP)
HIGUCHI GENKI (JP)
Application Number:
PCT/JP2023/016741
Publication Date:
November 02, 2023
Filing Date:
April 27, 2023
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
International Classes:
C07K2/00
Domestic Patent References:
| WO2022025209A1 | 2022-02-03 | |||
| WO2020171161A1 | 2020-08-27 |
Other References:
MURAOKA TAKAHIRO: "Amphiphilic Peptides with Flexible Chains for Tuning Supramolecular Morphologies, Macroscopic Properties and Biological Functions", J. SYNTH. ORG. CHEM., vol. 79, no. 11, 1 January 2021 (2021-01-01), pages 1033 - 1040, XP093103024, DOI: 10.5059/yukigoseikyokaishi.79.1033
JAMES D.ANDREW, BURNS DARCY C., WOOLLEY G.ANDREW: "Kinetic characterization of ribonuclease S mutants containing photoisomerizable phenylazophenylalanine residues", PROTEIN ENGINEERING, DESIGN AND SELECTION, OXFORD JOURNAL, LONDON, GB, vol. 14, no. 12, 1 December 2001 (2001-12-01), GB , pages 983 - 991, XP093103027, ISSN: 1741-0126, DOI: 10.1093/protein/14.12.983
SHIRAKI KENTARO: "Effect of additives on protein aggregation and liquid-liquid phase separation", BIOENGINEERING, vol. 98, no. 5, 1 January 2020 (2020-01-01), pages 251 - 254, XP093103204
JAMES D.ANDREW, BURNS DARCY C., WOOLLEY G.ANDREW: "Kinetic characterization of ribonuclease S mutants containing photoisomerizable phenylazophenylalanine residues", PROTEIN ENGINEERING, DESIGN AND SELECTION, OXFORD JOURNAL, LONDON, GB, vol. 14, no. 12, 1 December 2001 (2001-12-01), GB , pages 983 - 991, XP093103027, ISSN: 1741-0126, DOI: 10.1093/protein/14.12.983
SHIRAKI KENTARO: "Effect of additives on protein aggregation and liquid-liquid phase separation", BIOENGINEERING, vol. 98, no. 5, 1 January 2020 (2020-01-01), pages 251 - 254, XP093103204
Attorney, Agent or Firm:
MATSUNUMA Yasushi et al. (JP)
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