Title:
COMPOUNDS AS SUMO ACTIVATING ENZYME INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2024/099438
Kind Code:
A1
Abstract:
Disclosed in the present invention are compounds as SUMO activating enzyme inhibitors. Particularly, the present invention relates to compounds as represented by general formula (1) and general formula (2) and preparation methods therefor, and uses of the compounds of general formula (1) and general formula (2), and isomers thereof, crystal forms thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof as SAE inhibitors. The compounds and the isomers, crystal forms, pharmaceutically acceptable salts, hydrates or solvates thereof in the present invention can be used for preparing drugs for treating or preventing diseases related to SAE proteins.
Inventors:
XIE YULI (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
Application Number:
PCT/CN2023/131049
Publication Date:
May 16, 2024
Filing Date:
November 10, 2023
Export Citation:
Assignee:
WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN)
International Classes:
C07D495/10; A61K31/506; A61P35/00; A61P35/02; A61P35/04; C07D409/14; C07D419/14; C07D471/04; C07D513/10; C07D515/10
Foreign References:
| CN106999479A | 2017-08-01 | |||
| CN101379061A | 2009-03-04 | |||
| CN101516850A | 2009-08-26 | |||
| CN105492429A | 2016-04-13 | |||
| KR20170120521A | 2017-10-31 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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