Title:
COMPOUNDS AND COMPOSITIONS AS INDUCERS OF KERATINOCYTE DIFFERENTIATION
Document Type and Number:
WIPO Patent Application WO/2005/107760
Kind Code:
A1
Abstract:
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to induce undifferentiated keratinocytes to differentiate into terminally differentiated keratinocytes. The invention further provides compounds for the treatment of diseases or disorders associated with casein kinase II (CK2), TANK-binding kinase 1 (TBK1) and NIMA-related kinase 9 (NEK9).
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Inventors:
HONG JIYONG (US)
GRAY NATHANAEL S (US)
SCHULTZ PETER (US)
GRAY NATHANAEL S (US)
SCHULTZ PETER (US)
Application Number:
PCT/US2005/015118
Publication Date:
November 17, 2005
Filing Date:
April 29, 2005
Export Citation:
Assignee:
IRM LLC (US)
HONG JIYONG (US)
GRAY NATHANAEL S (US)
SCHULTZ PETER (US)
HONG JIYONG (US)
GRAY NATHANAEL S (US)
SCHULTZ PETER (US)
International Classes:
A61K31/4745; A61K31/519; C07D487/04; C07D491/02; C07D498/02; (IPC1-7): A61K31/519; A61K31/4745; C07D491/02; C07D498/02
Foreign References:
| US20030207900A1 | 2003-11-06 |
Attorney, Agent or Firm:
Reid, Scott W. (10675 John Jay Hopkins Drive San Diego, CA, US)
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