Title:
COMPOUNDS HAVING GLUTATHIONE PEROXIDASE ACTIVITY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO1991001125
Kind Code:
A3
Abstract:
The present invention provides compounds having glutathione peroxidase activity and, therefore, are effective glutathione peroxidase replacements. These compounds are useful as drugs for the prevention of cataracts and as anti-oxidants for H2O2 and other peroxides. The present invention also provides methods and pharmaceutical compositions of the compound.
Inventors:
SPECTOR ABRAHAM (US)
WILSON STEPHEN R (US)
ZUCKER PAUL A (US)
WILSON STEPHEN R (US)
ZUCKER PAUL A (US)
Application Number:
PCT/US1990/003963
Publication Date:
March 21, 1991
Filing Date:
July 17, 1990
Export Citation:
Assignee:
UNIV COLUMBIA (US)
UNIV NEW YORK (US)
UNIV NEW YORK (US)
International Classes:
C07C391/02; (IPC1-7): A61K/
Foreign References:
| US4910313A | 1990-03-20 | |||
| US4730053A | 1988-03-08 |
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