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Patent Searching and Data


Title:
COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS
Document Type and Number:
WIPO Patent Application WO2004101752
Kind Code:
A3
Abstract:
Novel acyl urea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory diseases, immunological diseases and cancer.

Inventors:
NEOGI PARTHA (US)
DEY DEBEDRANATH (US)
FULLER JOSEPH C (US)
CHEN LIANG (US)
LI TA-KAI (US)
Application Number:
US2004014394W
Publication Date:
February 16, 2006
Filing Date:
May 07, 2004
Export Citation:
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Assignee:
THERACOS INC (US)
NEOGI PARTHA (US)
DEY DEBEDRANATH (US)
FULLER JOSEPH C (US)
CHEN LIANG (US)
LI TA-KAI (US)
International Classes:
A61P3/10; C07C235/34; C07C271/64; C07C275/50; C07C281/06; C07C317/22; C07D213/56; C07D213/643; C07D213/75; C07D295/185; C07D213/64; C12N; (IPC1-7): A61K31/17; C07C303/00; C07C335/00
Foreign References:
US6646004B12003-11-11
Other References:
See also references of EP 1625207A4
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