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Title:
CONDENSED RING COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2005/014543
Kind Code:
A1
Abstract:
A condensed ring compound of the general formula: [I] (wherein the symbols are as defined in the description), etc. or a pharmaceutically acceptable salt thereof. There are further provided a hepatitis C virus (HCV) polymerase inhibitor and therapeutic agent for hepatitis C comprising the compound. This compound exhibits anti-HCV activity through HCV polymerase inhibiting activity and is thus useful as a therapeutic or preventive agent for hepatitis C.

Inventors:
OKA TAKAHIRO (JP)
YATA SHINJI (JP)
IKEGASHIRA KAZUTAKA (JP)
NOJI SATORU (JP)
AKAKI TATSUO (JP)
HIRASHIMA SHINTARO (JP)
NIWA YASUSHI (JP)
ANDO IZURU (JP)
SATO TOSHIHIRO (JP)
Application Number:
PCT/JP2004/011640
Publication Date:
February 17, 2005
Filing Date:
August 06, 2004
Export Citation:
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Assignee:
JAPAN TOBACCO INC (JP)
OKA TAKAHIRO (JP)
YATA SHINJI (JP)
IKEGASHIRA KAZUTAKA (JP)
NOJI SATORU (JP)
AKAKI TATSUO (JP)
HIRASHIMA SHINTARO (JP)
NIWA YASUSHI (JP)
ANDO IZURU (JP)
SATO TOSHIHIRO (JP)
International Classes:
A61K31/404; A61K31/405; A61K31/41; A61K31/4178; A61K31/4184; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/506; A61K31/5383; A61K31/541; C07D209/12; (IPC1-7): C07D209/08; A61K31/404; A61K31/405; A61K31/41; A61K31/4178; A61K31/4184; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/506; A61K31/5383; A61K31/541; C07D209/10; C07D209/12; C07D209/14; C07D209/24; C07D235/18; C07D401/12; C07D403/04; C07D403/06; C07D403/12; C07D405/04; C07D405/12; C07D405/14; C07D409/04; C07D409/12; C07D413/04; C07D413/06; C07D413/12; C07D413/14; C07D417/04; C07D417/12; C07D417/14; C07D471/04
Domestic Patent References:
WO2003010140A22003-02-06
WO2003010141A22003-02-06
WO2002004425A22002-01-17
WO2004065367A12004-08-05
WO2004064925A12004-08-05
Foreign References:
JP2003212846A2003-07-30
JP2001247550A2001-09-11
Attorney, Agent or Firm:
Takashima, Hajime (1-1 Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, JP)
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