Title:
CONSTRUCTION OF ENGINEERED EXTRACELLULAR VESICLE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067451
Kind Code:
A1
Abstract:
The present invention provides an engineered extracellular vesicle, a pharmaceutical composition containing the engineered extracellular vesicle and a use thereof, and further provides a method for constructing the engineered extracellular vesicle. The engineered extracellular vesicle can be used for drug delivery, enrichment of target proteins in extracellular vesicles, or display of target proteins.
Inventors:
ZHAO LIBO (CN)
KONG GUANYI (CN)
LI HONGYAN (CN)
GUAN HONGTAO (CN)
WANG JIANWU (CN)
ZHAO HANG (CN)
YOU ZHICHENG (CN)
LIU DA (CN)
LIN ZHONGQING (CN)
LI ZHI (CN)
CHEN JING (CN)
KONG GUANYI (CN)
LI HONGYAN (CN)
GUAN HONGTAO (CN)
WANG JIANWU (CN)
ZHAO HANG (CN)
YOU ZHICHENG (CN)
LIU DA (CN)
LIN ZHONGQING (CN)
LI ZHI (CN)
CHEN JING (CN)
Application Number:
PCT/CN2023/120966
Publication Date:
April 04, 2024
Filing Date:
September 25, 2023
Export Citation:
Assignee:
BEIJING ECHO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K19/00; A61K38/00; A61K39/00; C12N15/62
Foreign References:
| US20200088734A1 | 2020-03-19 | |||
| CN109689097A | 2019-04-26 | |||
| CN111212632A | 2020-05-29 | |||
| US20160137716A1 | 2016-05-19 | |||
| CN104053451A | 2014-09-17 |
Other References:
LYDIA ALVAREZ-ERVIT ET AL.: "Delivery of siRNA to the Mouse Brain by Systemic Injection of Targeted Exosomes", NATURE BIOTECHNOLOGY, vol. 29, no. 4, 30 April 2011 (2011-04-30), XP055554900, DOI: 10.1038/nbt.1807
MENG WANRONG: "Prospects and challenges of exosomes as drug delivery systems", JOURNAL OF BIOMEDICAL ENGINEERING, vol. 37, no. 4, 22 July 2020 (2020-07-22), pages 714 - 720, XP093152233, DOI: 10.7507/1001-5515.201810027
MENG WANRONG: "Prospects and challenges of exosomes as drug delivery systems", JOURNAL OF BIOMEDICAL ENGINEERING, vol. 37, no. 4, 22 July 2020 (2020-07-22), pages 714 - 720, XP093152233, DOI: 10.7507/1001-5515.201810027
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW CO., LTD. (CN)
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