Title:
CONTROLLED RELEASE COMPOSITION FOR PHYSIOLOGICALLY ACTIVE SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2013/073454
Kind Code:
A2
Abstract:
[Problem] To provide a controlled release composition for a physiologically active substance, with which it is possible to start release of the physiologically active substance in vivo with the necessary timing. [Solution] The composition comprises an inner layer made from a biodegradable substance that supports the physiologically active substance, and an outer layer, which is made from a biodegradable material different to that of the inner layer.
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Inventors:
NAKAJI TADASHI (JP)
KITANO HIROMI (JP)
GUJRAL CHIRAG HARSHARAN SINGH (JP)
KITANO HIROMI (JP)
GUJRAL CHIRAG HARSHARAN SINGH (JP)
Application Number:
PCT/JP2012/079062
Publication Date:
May 23, 2013
Filing Date:
November 09, 2012
Export Citation:
Assignee:
NAT UNIV CORP UNIV TOYAMA (JP)
International Classes:
A61K9/24; A61K9/26; A61K45/00; A61K47/34; A61K47/42; A61K47/48; A61L27/00
Foreign References:
| JPH08225454A | 1996-09-03 | |||
| JPH08253426A | 1996-10-01 | |||
| JPH07236688A | 1995-09-12 | |||
| EP2351556A2 | 2011-08-03 |
Other References:
MADDURI,S. ET AL.: 'Effect of controlled co- delivery of synergistic neurotrophic factors on early nerve regeneration in rats' BIOMATERIALS vol. 31, no. 32, 2010, pages 8402 - 8409
MADDURI,S. ET AL.: 'Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF' J CONTROL RELEASE vol. 143, no. 2, 2010, pages 168 - 174
MADDURI,S. ET AL.: 'Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF' J CONTROL RELEASE vol. 143, no. 2, 2010, pages 168 - 174
Attorney, Agent or Firm:
OTANI Kaichi (JP)
Kaichi Otani (JP)
Kaichi Otani (JP)
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Claims: