Title:
CONTROLLED-RELEASE TICAGRELOR TABLET AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/223480
Kind Code:
A1
Abstract:
Provided are a controlled-release ticagrelor tablet and a preparation method therefor, wherein the controlled-release tablet comprises a tablet core and a film-controlled coating system, the tablet core comprises ticagrelor accounting for 30‑60 wt％ of the total weight of the tablet core, and the controlled-release tablet is provided with two or more drug release holes. The controlled-release ticagrelor tablet is mild and long-lasting in release, can be released almost completely within 20 h, can have a good release effect on ticagrelor of different crystal forms, and is also stable in performance, can be stored for a long time, and has a simple preparation process and is suitable for industrial production.
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| WO/2005/030180 | OSMOTIC DOSAGE FORMS FOR CONTROLLED DELIVERY OF ALPRAZOLAM |
| JPH0578233 | MEDICINAL CONTAINING GRANULE |
| WO/2005/070417 | COMPRESSION COATED TABLET COMPRISING SUMATRIPTAN |
Inventors:
SHU XIN (CN)
DONG HAIHONG (CN)
CHEN LEI (CN)
LU PINGBO (CN)
DONG HAIHONG (CN)
CHEN LEI (CN)
LU PINGBO (CN)
Application Number:
PCT/CN2021/075842
Publication Date:
November 11, 2021
Filing Date:
February 07, 2021
Export Citation:
Assignee:
JIANGSU ALICORN PHARMATECH CO LTD (CN)
International Classes:
A61K9/44; A61K31/519; A61K47/10; A61K47/12; A61K47/26; A61K47/38; A61P7/02
Foreign References:
| CN111450072A | 2020-07-28 | |||
| CN111991362A | 2020-11-27 | |||
| CN103860504A | 2014-06-18 | |||
| CN1579370A | 2005-02-16 | |||
| CN110507624A | 2019-11-29 | |||
| CN108210498A | 2018-06-29 | |||
| CN102657629A | 2012-09-12 | |||
| CN110876732A | 2020-03-13 | |||
| US20190070181A1 | 2019-03-07 |
Other References:
REN, JUNGANG : "Research Progress on Preparing Process of Monolayer Osmotic Pump Tablets for Insoluble Drugs", HEILONGJIANG MEDICINE JOURNAL, vol. 26, no. 3, 15 June 2013 (2013-06-15), CN, pages 430 - 432, XP009531605, ISSN: 1006-2882, DOI: 10.14035/j.cnki.hljyy.2013.03.007
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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