Isabella grape (Vitis Labrusca L.), known as "Scented Grape, Fragrant Black Grape", is a grape variety native to the eastern Black Sea region. It is also known as Black Grape, Macir Grape, Strawberry Grape and Favli Grape depending on the region. Isabella grape is resistant to fungal diseases that can occur in its own kind. When fully matured, it turns into a dark color like black- purple. Generally, they complete their maturation in August and October. Despite having a thick skin, Isabella Grape separates easily and, as the name suggests, emits a very pleasant scent after separation. After its maturation is completed, it is collected and made of must, vinegar and molasses. Resveratrol (Formula I), which is found in the skin of Isabella grapes, is a polyphenol compound and is found at a high amount in Isabella.

Anti-wrinkle and moisturizing creams have been known for hundreds of years. Cosmetics alike this products are applied to the skin with the aim of moisturizing and/or preventing or eliminating the appearance of wrinkles or other undesirable conditions. With this,

These cosmetics often contain abrasives that are used to remove wrinkles and blemishes from the outer layer of the skin. There are currently a large number of cosmetic formulations for skin treatment on the market, However, considering their chemical composition, there are many products that tend to cause allergies, and in terms of efficacy, in most cases the results are not as stated. While some plant extracts and chemicals have been used to create an anti-wrinkle and anti-blemish composition, most have had limited success.

Brief Description of the Invention

Isabella grapes, unlike the other grapes, have a very aromatic odor. Extracts from Isabella grape cream might be used for skin protection, removal of redness, blemishes and wrinkles in topical formulations and also it can be used as a natural compound to give a good smell with anti-aging activity. The cosmetic preparation according to the invention contains the extract of Isabella grapes. For extract extraction; After squeezing the juice of the grapes, the pulp is mixed with alcohol, glycerin, water or their mixtures. extraction is done. It is obtained with glycerin and water preferably in cosmetic formulation. The extract that used in the cosmetic preparation is preferably in the form of a topically use cream. Cyanidin 3-glucoside (Chryanthemine) (Formula II), an extract anthocyanin Chryanthemine compound is responsible for removing redness and blemishes on the skin, anti-aging activity and skin care effects. Detailed Description of the Invention

The invention relates to cosmetic preparations containing Isabella grape extract that can be used on the face, skin and eye area. The cosmetic preparation of the invention is in the form of cream, soap, lotion, body creams, gel, emulsion, solution, spray, serum, mask or foam. Cosmetic preparation is preferably in cream form. There may be creams containing liposomes and creams containing microspheres. Extraction of Isabella grapes can be done with alcohol, glycerin, water or mixtures.

Preferably the extraction solution is a glycerine - water mixture. To prepare Isabella grape extract, 50-75% glycerin by volume and 50-25% distilled water are used. For example, an extraction solution containing 70% glycerine by volume with 30% water can be used. In addition, the glycerine-water ratio can be 50-50%, 55-45%, 60-40%, 65-35%, 75-25% by volume. Glycerin - previously crushed with a mixture of water and the pulp of Isabella grapes, the juice of which has been separated, is extracted and filtered to obtain a red-burgundy solution. The resulting solution is used for the production of cosmetic formulation. Before extraction, the grape pulp can be dried if desired. The extract contains Cyanidin 3-glucoside (Chryanthemine) (Formula II). Anthocyanins protect cells against oxidative stress and DNA damage. Due to its high anthocyanin content, the extract of Isabella grapes is useful in the formulation of the phytocosmetic preparation of the invention. Chryanthemine content of the extract to be used in the formulation is at least lOOOmg/kg according to the amount of pulp extracted.

To prepare semi-solid formulations such as cream, hydrocarbon bases such as white petrolatum, solid paraffin, beeswax, Absorption bases such as anhydrous lanolin, water-soluble bases such as polyethylene glycol, glycerin are used.

In semi-solid preparations, excipients with the following functions are also used:

• Ethyl paraben (or sodium salt), Propyl paraben (or sodium salt), Methyl paraben (or sodium salt) salt, Sorbic acid (or sodium, potassium, calcium salt), Benzoic acid (or sodium, potassium, calcium salt), Sulfur dioxide (sodium sulphite, sodium hydrogensulfite, sodium 'metabisulfite', potassium metabisulfite, calcium sulfide, calcium hydrogen sulfite), Potassium hydrogensulfite, glutaraldehyde, chlorobutanol, benzalkonium chloride, Biphenyl, 2-Hydroxybiphenyl, Sodium biphenyl-2-yl oxide, Thiabendazole, Antimicrobial protectors such as Hexamine, Potassium nitrite, Sodium nitrite, Sodium nitrate, Potassium nitrate, Propionic acid (plus sodium, calcium, potassium salts), Nisin, triclosan phenethylalcohol,

• Antioxidants such as Butylated hydroxyanisole (BHA), Butylated hydroxytoluene (BHT)l- ascorbic acid, Sodium 1-ascorbate Calcium 1-ascorbate ascorbyl palmitate Propyl gallate Octyl gallate Dodecyl gallate, Erythorbic acid Sodium erythorbate, a-tocopherol (antioxidant)

• Stabilizing agents such as EDTA,

• Viscosity increasers such as HPMC, HEC, CMC, Carbomer, Acrylate copolymers, Alginate, Carragean, Xanthan gum,

• Surfactants such as polysorbates, sorbitan esters, poloxamers, penetration enhancers,

• Fragrance and coloring agents. Sample Formulation

Stearyl alcohol %10 Cetyl alcohol %5 Glycerine %5 Isabella Extract %l-20

Methyl paraben %0.01

Distilled water adequate amount for % 100 of final cream formulation

Cosmetic cream can be applied day and night. Daily use gives the skin, neck and hands youth and freshness, a relaxed face and a feeling of well-being.