Title:
CRYSTAL FORM OF COMPOUND INHIBITING FUNCTION OF ADAMTS-5 AND/OR ADAMTS-4, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/011547
Kind Code:
A1
Abstract:
The present disclosure relates to a crystal form of a compound inhibiting the function of ADAMTS-5 and/or ADAMTS-4, and preparation method therefor and the use thereof. Specifically, the present disclosure relates to a crystal of and a preparation method for compound A of formula I and the use thereof in the treatment of diseases involving cartilage degradation or disruption of cartilage homeostasis, such as osteoarthritis and/or rheumatoid arthritis.
Inventors:
HAN LONG (CN)
SHAO QIYUN (CN)
FENG JUN (CN)
HE FENG (CN)
SHAO QIYUN (CN)
FENG JUN (CN)
HE FENG (CN)
Application Number:
PCT/CN2022/110038
Publication Date:
February 09, 2023
Filing Date:
August 03, 2022
Export Citation:
Assignee:
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D233/76; A61K31/4166; A61K31/417; A61P19/04; C07D233/78; C07D401/12
Domestic Patent References:
| WO2021158626A1 | 2021-08-12 | |||
| WO2021204185A1 | 2021-10-14 |
Foreign References:
| CN113754635A | 2021-12-07 | |||
| CN107108579A | 2017-08-29 | |||
| US20190300503A1 | 2019-10-03 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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