Title:
CRYSTAL FORM OF RAF KINASE INHIBITOR AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/253334
Kind Code:
A1
Abstract:
Provided are a crystal form of a RAF kinase inhibitor and a preparation method therefor. Specifically disclosed are a compound N-(3-(2-((1R,5S)-3-oxabicyclo[3.1.0]hex-1-yl)-6-(2-hydroxyethoxy)pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl) isnicotinamide of formula (I) and a preparation method therefor.
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Inventors:
LIU XILE (CN)
DING CHARLES Z (CN)
CHEN SHUHUI (CN)
HU LIHONG (CN)
ZHOU CHENGLIANG (CN)
SUN DEHENG (CN)
DING CHARLES Z (CN)
CHEN SHUHUI (CN)
HU LIHONG (CN)
ZHOU CHENGLIANG (CN)
SUN DEHENG (CN)
Application Number:
PCT/CN2022/096983
Publication Date:
December 08, 2022
Filing Date:
June 02, 2022
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D405/14; A61K31/444; A61P35/00
Domestic Patent References:
| WO2021110141A1 | 2021-06-10 | |||
| WO2020230028A1 | 2020-11-19 |
Foreign References:
| CN113912591A | 2022-01-11 | |||
| CN107074828A | 2017-08-18 | |||
| CN109310761A | 2019-02-05 | |||
| CN111465598A | 2020-07-28 | |||
| CN105143209A | 2015-12-09 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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