CRYSTAL FORM OF TAFAMIDIS AND PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

CRYSTAL FORM OF TAFAMIDIS AND PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/093809

Kind Code:

A1

Abstract:

Disclosed are a new crystal form of tafamidis (compound I) and a preparation method therefor, a pharmaceutical composition containing the crystal form, and use of the crystal form in the preparation of a drug for treating diseases caused by transthyretin amyloidosis. The crystalline form of tafamidis has one or more improved properties compared with the prior art, and is of great value to the optimization and development of the drug in the future.

More Like This:

WO/2015/047982	KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
JP2008530210	Use of estrogen receptor-β-selective agonists for radiation or chemotherapy-induced mucositis and radiation cystitis
JP2802547	INDUSTRIAL APPLICABILITY The isoxazoline compound as an anti-inflammatory agent

Inventors:

CHEN MINHUA (CN)
ZHANG JING (CN)
ZOU SIMING (CN)

Application Number:

PCT/CN2020/128376

Publication Date:

May 20, 2021

Filing Date:

November 12, 2020

Export Citation:

Click for automatic bibliography generation Help

Assignee:

CRYSTAL PHARMACEUTICAL SUZHOU CO LTD (CN)

International Classes:

A61K31/423; C07D263/57; A61P25/00

Domestic Patent References:

WO2019175263A1	2019-09-19
WO2016038500A1	2016-03-17
WO2019175263A1	2019-09-19

Foreign References:

CN107344927A	2017-11-14
CN103781770A	2014-05-07
CN106715405A	2017-05-24

Other References: