Title:
CRYSTALLINE FORM OF NICOTINAMIDE RIBOSIDE
Document Type and Number:
WIPO Patent Application WO/2016/014927
Kind Code:
A3
Abstract:
Provided are crystalline forms of nicotinamide riboside, including a Form I of nicotinamide riboside chloride according to formula (I). Also disclosed are pharmaceutical compositions comprising the crystalline Form I of nicotinamide riboside chloride, and methods of producing such pharmaceutical compositions. In other aspects, the present disclosure pertains to methods comprising administering to a subject the crystalline Form I of nicotinamide riboside chloride. The present disclosure also provides methods of preparing the crystalline Form I of nicotinamide riboside chloride. Also provided are a crystalline Form I of nicotinamide riboside chloride that is prepared according to any of the disclosed methods for preparing the crystalline Form I.
Inventors:
CARLSON ERIK C (US)
STANDEN MICHAEL C (US)
MORRILL WESTIN M (US)
STANDEN MICHAEL C (US)
MORRILL WESTIN M (US)
Application Number:
PCT/US2015/041956
Publication Date:
September 15, 2016
Filing Date:
July 24, 2015
Export Citation:
Assignee:
W R GRACE & CO -CONN (US)
International Classes:
C07H19/04; A61K45/06
Foreign References:
| US20120172584A1 | 2012-07-05 | |||
| US20110306597A1 | 2011-12-15 | |||
| US20050020587A1 | 2005-01-27 | |||
| US20080146569A1 | 2008-06-19 | |||
| US20060229265A1 | 2006-10-12 | |||
| US20050267023A1 | 2005-12-01 | |||
| US20120329748A1 | 2012-12-27 |
Other References:
See also references of EP 3174891A4
Attorney, Agent or Firm:
LEVIN, Gary, H. et al. (2929 Arch Street12th Floor, Cira Centr, Philadelphia PA, US)
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