CRYSTALS OF THIADIAZOLE DERIVATIVE DPP-IV INHIBITORS AND USES THEREOF

WIPO Patent Application WO/2017/088790

A1

The present invention belongs to the field of drug crystals, relates to crystals of thiadiazole derivative DPP-IV inhibitors, and in particular relates to A and B type crystals of the compound as shown in formula 7. The crystals of the present invention have excellent stability. For example, under high temperature, high humidity or light test conditions, the material contents associated with the crystal of the compound of formula 7 do not change significantly. In addition, the crystal of the present invention also has a very good powder flowability and satisfies the requirements of drug preparation and production.

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PENG YAN (CN)
LIU FEI (CN)
CHEN ZHILIN (CN)
ZHANG YAYU (CN)
HU ZHONGYUAN (CN)
JIANG JINFENG (CN)

PCT/CN2016/107076

June 01, 2017

November 24, 2016

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CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
CENTAURUS BIOPHARMA CO LTD (CN)

C07D519/00; A61K31/522; A61P3/10

CN102807568A	2012-12-05
CN102807568A	2012-12-05
CN102807568A	2012-12-05

"Pharmaceutics"
"Chinese Pharmacopoeia", 2010

INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)

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