Title:
CULTURE MEANS FOR SYNTHESIZING SACCHAROMYCES CEREVISIAE CAROTENOID
Document Type and Number:
WIPO Patent Application WO/2021/259384
Kind Code:
A1
Abstract:
Provided is a fermentation culture medium beneficial for the synthesis of Saccharomyces cerevisiae carotenoid, the medium comprising a basic culture medium for Saccharomyces cerevisiae, and copper ions. The fermentation culture medium is used to improve the accumulation of recombinant Saccharomyces cerevisiae carotenoid. A synergistic enhancement effect present between zinc ions and the copper ions in the culture medium is shown from a transcriptome, and the synthesis of carotenoid can be significantly improved by means of adding the two.
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Inventors:
ZHU HONGHUI (CN)
SU BULI (CN)
WANG DONGDONG (CN)
LI ANZHANG (CN)
DENG MINGRONG (CN)
FENG GUANGDA (CN)
SU BULI (CN)
WANG DONGDONG (CN)
LI ANZHANG (CN)
DENG MINGRONG (CN)
FENG GUANGDA (CN)
Application Number:
PCT/CN2021/108449
Publication Date:
December 30, 2021
Filing Date:
July 26, 2021
Export Citation:
Assignee:
INST OF MICROBIOLOGY GUANGDONG ACADEMY OF SCIENCES GUANGDONG DETECTION CENTER OF MICROBIOLOGY (CN)
International Classes:
C12N1/38; C12N1/18; C12N15/31; C12P23/00
Foreign References:
| CN112553096A | 2021-03-26 | |||
| CN110982721A | 2020-04-10 | |||
| CN110144300A | 2019-08-20 |
Other References:
"Doctoral Dissertation", 1 May 2017, SHANGHAI PHARMACEUTICAL INDUSTRY RESEARCH INSTITUTE, article YIN SHENGMING: "Study on Production of β-carotene by Engineering of Yarrowia Lipolytica", pages: 1 - 152, XP055882900
ZHANG YING-XIN, XIN JIA-YING, LIU SHU-JUAN, DONG JING: "Effect of metal ion on carotenoid production by Rhodotorula sp.", SCIENCE AND TECHNOLOGY OF FOOD INDUSTRY, GAI KAN BIANJIBU , BEIJING, CN, vol. 31, no. 1, 25 January 2010 (2010-01-25), CN , pages 65 - 67+70, XP055882906, ISSN: 1002-0306, DOI: 10.13386/j.issn1002-0306.2010.01.041
ANONYMOUS: "Effects of metal cations on fermentation of Saccharomyces cerevisiae J-31", GLOBAL ALCINFO, no. 13, 10 July 2017 (2017-07-10), pages 24 - 30, XP055882911, ISSN: 2096-0972
ZHANG YING-XIN, XIN JIA-YING, LIU SHU-JUAN, DONG JING: "Effect of metal ion on carotenoid production by Rhodotorula sp.", SCIENCE AND TECHNOLOGY OF FOOD INDUSTRY, GAI KAN BIANJIBU , BEIJING, CN, vol. 31, no. 1, 25 January 2010 (2010-01-25), CN , pages 65 - 67+70, XP055882906, ISSN: 1002-0306, DOI: 10.13386/j.issn1002-0306.2010.01.041
ANONYMOUS: "Effects of metal cations on fermentation of Saccharomyces cerevisiae J-31", GLOBAL ALCINFO, no. 13, 10 July 2017 (2017-07-10), pages 24 - 30, XP055882911, ISSN: 2096-0972
Attorney, Agent or Firm:
GUANGZHOU KEYUE I.P. LAW OFFICE (CN)
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