Title:
CULTURE MEDIUM COMPOSITION FOR FAECALIBACTERIUM PRAUSNITZII STRAIN
Document Type and Number:
WIPO Patent Application WO/2023/090536
Kind Code:
A1
Abstract:
The present invention relates to a medium composition for culturing Faecalibacterium prausnitzii, and a method for mass-culturing Faecalibacterium prausnitzii by using same, the composition containing vegetable-peptone, a yeast extract, a phosphate compound, a carbonate compound, cyanocobalamin (B12), L-cysteine, ammonium acetate and maltose. A medium composition and a method for culturing Faecalibacterium prausnitzii, according to the present invention, enable the high cell-density culture and mass production of Faecalibacterium prausnitzii pylogroup II strains. In addition, since animal ingredients are excluded and high cell-density culture is possible even under high concentration of anaerobic nitrogen gas during mass production, a more economical and industrialization-appropriate culture method can be provided.
Inventors:
SEO JAE GU (KR)
LEE DO KYUNG (KR)
LEE DO KYUNG (KR)
Application Number:
PCT/KR2022/001867
Publication Date:
May 25, 2023
Filing Date:
February 07, 2022
Export Citation:
Assignee:
ENTEROBIOME INC (KR)
International Classes:
C12N1/20
Foreign References:
| KR102222953B1 | 2021-03-04 | |||
| KR102245415B1 | 2021-04-29 | |||
| KR100218233B1 | 1999-10-01 | |||
| US20190298782A1 | 2019-10-03 | |||
| US8012716B2 | 2011-09-06 | |||
| KR102245415B1 | 2021-04-29 | |||
| KR102169794B1 | 2020-10-27 |
Other References:
LOPEZ-SILES ET AL., APPL ENVIRON MICROBIOL., vol. 78, 2012, pages 420 - 428
MACHTEL ET AL., RES. MICROBIOL., vol. 190, 2019, pages 321 - 337
KILLAM ET AL., J. CLIN. MICROBIOL., vol. 41, 2003, pages 2201 - 2202
REILLY ET AL., J. MED. MICROBIOL., vol. 13, 1980, pages 573 - 579
STALONS ET AL., APPL. MICROBIOL., vol. 27, 1974, pages 1098 - 1104
MACHTEL ET AL., RES. MICROBIOL., vol. 190, 2019, pages 321 - 337
KILLAM ET AL., J. CLIN. MICROBIOL., vol. 41, 2003, pages 2201 - 2202
REILLY ET AL., J. MED. MICROBIOL., vol. 13, 1980, pages 573 - 579
STALONS ET AL., APPL. MICROBIOL., vol. 27, 1974, pages 1098 - 1104
Attorney, Agent or Firm:
PARK, Hyuk (KR)
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