CYCLIC AMINE CCR3 ANTAGONISTS

Title:

CYCLIC AMINE CCR3 ANTAGONISTS

Document Type and Number:

WIPO Patent Application WO/2001/010439

Kind Code:

A1

Abstract:

Drugs containing as the active ingredient cyclic amine derivatives represented by general formula (I), pharmaceutically acceptable acid addition salts thereof or pharmaceutically acceptable C¿1-6? alkyl adducts thereof. These drugs are efficacious in preventing and treating diseases in which CCR3 participates such as asthma and allergic rhinitis.

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Inventors:

SHIOTA TATSUKI (JP)
SUDOH MASAKI (JP)
YOKOYAMA TOMONORI (JP)
MUROGA YUMIKO (JP)
KAMIMURA TAKASHI (JP)
NAKANISHI AKINOBU (JP)

Application Number:

PCT/JP2000/005260

Publication Date:

February 15, 2001

Filing Date:

August 04, 2000

Export Citation:

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Assignee:

TEIJIN LTD (JP)
SHIOTA TATSUKI (JP)
SUDOH MASAKI (JP)
YOKOYAMA TOMONORI (JP)
MUROGA YUMIKO (JP)
KAMIMURA TAKASHI (JP)
NAKANISHI AKINOBU (JP)

International Classes:

A61K31/40; A61K31/445; A61P11/08; A61P29/00; A61P31/18; A61P37/08; A61P43/00; C07D207/14; (IPC1-7): A61K31/40; A61K31/4025; A61K31/445; A61K31/4468; A61K31/4525; A61K31/4535; A61K31/454; A61K31/422; A61K31/404; A61K31/4155; A61K31/4245; A61K31/5377; A61K31/4545; A61K31/4709; A61K31/4184; A61K31/427; A61K31/506; A61K31/433; A61K31/423; A61K31/4192; A61K31/429; A61K31/53; A61P37/08; A61P29/00; A61P31/18; A61P11/08; A61P43/00

Domestic Patent References:

WO1999025686A1	1999-05-27
WO1998050534A1	1998-11-12
WO1997040051A1	1997-10-30
WO2000031032A1	2000-06-02

Foreign References:

EP0217286A1	1987-04-08
GB2106108A	1983-04-07

Other References:

KHALID M. ET AL.: "N,N'-disubstituted L-isoglutamines as novel cancer chemotherapeutic agents", DRUGS EXP. CLIN. RES., vol. 13, no. (SUPPL. 1), 1987, pages 57 - 60, XP002933769
See also references of EP 1201239A4

Attorney, Agent or Firm:

Maeda, Sumihiro (Intellectual Property Center 1-1 Uchisaiwaicho 2-chome Chiyoda-ku, Tokyo, JP)

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