Title:
CYCLIC AMINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2010/016554
Kind Code:
A1
Abstract:
Disclosed is a compound represented by formula (Ia) [wherein each symbol is as defined in the description] or a salt thereof. The compound has an inhibitory activity on the reuptake of a monoamine, and is therefore useful as a therapeutic/prophylactic agent for depression, anxiety, attention-deficit/hyperactivity disorder, stress urinary incontinence and others, or the like.
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Inventors:
ISHICHI YUJI (JP)
KIMURA EIJI (JP)
TERAUCHI JUN (JP)
KIMURA EIJI (JP)
TERAUCHI JUN (JP)
Application Number:
PCT/JP2009/063964
Publication Date:
February 11, 2010
Filing Date:
August 06, 2009
Export Citation:
Assignee:
TAKEDA PHARMACEUTICAL (JP)
ISHICHI YUJI (JP)
KIMURA EIJI (JP)
TERAUCHI JUN (JP)
ISHICHI YUJI (JP)
KIMURA EIJI (JP)
TERAUCHI JUN (JP)
International Classes:
C07D211/20; A61K31/4465; A61K31/454; A61K31/495; A61K31/551; A61P13/02; A61P25/00; A61P25/14; A61P25/22; A61P25/24; A61P43/00; C07D211/22; C07D211/24; C07D211/26; C07D211/32; C07D211/34; C07D211/48; C07D243/08; C07D295/08; C07D295/10; C07D295/14; C07D401/06; C07D401/12; C07D413/06
Domestic Patent References:
| WO2007002057A1 | 2007-01-04 | |||
| WO2009089462A1 | 2009-07-16 |
Foreign References:
| JP2007509073A | 2007-04-12 | |||
| JP2007508393A | 2007-04-05 | |||
| US20050234058A1 | 2005-10-20 |
Other References:
DAVIDSON ET AL.: "New tissue schizontocidal antimalarial drugs", BULLETIN OF THE WORLD HEALTH ORGANIZATION, vol. 59, no. 3, 1981, pages 463 - 479
MCCAUSTLAND ET AL.: "Structural modification study of the antimalarial 2- (p-chlorophenyl)-2-(4-piperidyl) tetrahydrofuran", JOURNAL OF MEDICINAL CHEMISTRY, vol. 17, no. 9, 1974, pages 993 - 1000
PETERS, W. ET AL.: "The chemotherapy of rodent malaria. XXIII. Causal prophylaxis. II. Practical experience with Plasmodium yoelii nigeriensis in drug screening", ANNALS OF TROPICAL MEDICINE & PARASITOLOGY, vol. 69, no. 3, 1975, pages 311 - 328
GAUTAM, B. C. ET AL.: "Agents acting on the central nervous system. VI. 2-Tertiary- aminophenylacetic acid esters and 2-tertiary- amino-2-phenylethanols", INDIAN JOURNAL OF CHEMISTRY, vol. 4, no. 5, 1966, pages 239 - 243
CAVALLINI, G. ET AL.: "Basic 4-chlorophenyl- 4-pyridylcarbinol ethers new synthetic antihistaminics", FARMACO, EDIZIONE SCIENTIFICA, vol. 12, 1957, pages 887 - 891
SATO, YASUNOBU ET AL.: "Syntheses and pharmacology of 1-[2-(2-hydroxyethoxy)ethyl]-4- p- chlorobenzylpiperidine hydrochloride (piclobetol), and related compounds", ANN. SANKYO RES. LAB., vol. 23, 1971, pages 104 - 116
"THE MERCK MANUAL OF DIAGNOSIS AND THERAPY", SEVENTEENTH EDITION, MERCK RESEARCH LABORATORIES, 1999, pages 1531 - 1538
MCCAUSTLAND ET AL.: "Structural modification study of the antimalarial 2- (p-chlorophenyl)-2-(4-piperidyl) tetrahydrofuran", JOURNAL OF MEDICINAL CHEMISTRY, vol. 17, no. 9, 1974, pages 993 - 1000
PETERS, W. ET AL.: "The chemotherapy of rodent malaria. XXIII. Causal prophylaxis. II. Practical experience with Plasmodium yoelii nigeriensis in drug screening", ANNALS OF TROPICAL MEDICINE & PARASITOLOGY, vol. 69, no. 3, 1975, pages 311 - 328
GAUTAM, B. C. ET AL.: "Agents acting on the central nervous system. VI. 2-Tertiary- aminophenylacetic acid esters and 2-tertiary- amino-2-phenylethanols", INDIAN JOURNAL OF CHEMISTRY, vol. 4, no. 5, 1966, pages 239 - 243
CAVALLINI, G. ET AL.: "Basic 4-chlorophenyl- 4-pyridylcarbinol ethers new synthetic antihistaminics", FARMACO, EDIZIONE SCIENTIFICA, vol. 12, 1957, pages 887 - 891
SATO, YASUNOBU ET AL.: "Syntheses and pharmacology of 1-[2-(2-hydroxyethoxy)ethyl]-4- p- chlorobenzylpiperidine hydrochloride (piclobetol), and related compounds", ANN. SANKYO RES. LAB., vol. 23, 1971, pages 104 - 116
"THE MERCK MANUAL OF DIAGNOSIS AND THERAPY", SEVENTEENTH EDITION, MERCK RESEARCH LABORATORIES, 1999, pages 1531 - 1538
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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