Title:
CYCLIC DINUCLEOTIDE COVALENT MODIFIER, PREPARATION METHOD THEREFORAND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/012402
Kind Code:
A1
Abstract:
The present invention relates to a cyclic dinucleotide covalent modifier, a preparation method therefor and use thereof. Specifically, the present invention relates to a method for linking a linking arm to a compound shown in a formula SF, the method is to link the linking arm to S in phosphoryl sulfide of the compound shown in the formula SF,
Inventors:
LI YANMEI (CN)
WU JUNJUN (CN)
ZHAO LANG (CN)
CHEN YONGXIANG (CN)
WU JUNJUN (CN)
ZHAO LANG (CN)
CHEN YONGXIANG (CN)
Application Number:
PCT/CN2021/105136
Publication Date:
January 20, 2022
Filing Date:
July 08, 2021
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
International Classes:
C07H1/00; A61K31/7084; A61K45/06; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/02; C07H21/00; C07H21/04
Domestic Patent References:
| WO2019129880A1 | 2019-07-04 | |||
| WO2019183578A1 | 2019-09-26 | |||
| WO2019051489A1 | 2019-03-14 |
Foreign References:
| CN111909223A | 2020-11-10 | |||
| CN109843302A | 2019-06-04 | |||
| CN107148424A | 2017-09-08 | |||
| CN110461416A | 2019-11-15 |
Other References:
WU JUNJUN, LANG ZHAO, HONG-GUO HU, WEN-HAO LI, YAN-MEI LI : "Agonists and inhibitors of the STING pathway: Potential agents for immunotherapy", MED RES REV, vol. 40, no. 3, 2 December 2019 (2019-12-02), pages 1117 - 1141, XP055886574, DOI: 10.1002/med.21649
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)
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