CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF

Title:

CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2015/027959

Kind Code:

A1

Abstract:

The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.

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Inventors:

JIANG SHENG (CN)
YAO ZHIYI (CN)
YAO YIWU (CN)
QIU YATAO (CN)
LU CHANGYIN (CN)
SU KUN (CN)
YAO XIAOMING (CN)

Application Number:

PCT/CN2014/085705

Publication Date:

March 05, 2015

Filing Date:

September 02, 2014

Export Citation:

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Assignee:

SHANGHAI GUANYU BIO MEDICAL CO LTD (CN)

International Classes:

C07K5/12; A61K38/06; A61P25/28; A61P31/18; A61P33/06; A61P35/00; A61P35/02; A61P35/04; C07K1/06

Foreign References:

CN102391359A	2012-03-28
CN102391359A	2012-03-28

Other References: